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Obesity-Initiated Metabolic Syndrome and the Kidney: A Recipe for Chronic Kidney Disease?

by: Susan P Bagby

J Am Soc Nephrol, Vol. 15, No. 11. (1 November 2004), pp. 2775-2791.

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10.1097/01.ASN.0000141965.28037.EE

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1 11beta-hsd1 2 4 5q-_syndrome 88 9 a2b abdominal_surgery abx acetaminophen acid acid-base acids actin activator acute adaptor adipocytes adipokine adiponectin adipose age aged agents airway aki alanine aliskiren ampk analgesics anca and animals annual2004 antibodies antigens antimicrobial anti-obesity apoptosis aps aristolochic_acid arteriosclerosis assay at2r atherosclerosis atra b bac_transgenic barrier beta beta-catenin bile binding biological biomarker black_swan blocking blood_pressure blotting bone bone_marrow bronchoconstriction c3h c57bl c-akt calcification capd carbon carboxykinase carcinoma cardiovascular carrier carter cationic cattle c-bcl-6 ccl2 ccr2 cd14 cd16 cd44 cell cell-cycle cells chemokine chemokines chemotaxis cholesterol chorea cilia cirrhosis ckd clinical coculture common communication complement complementary creatinine cre_loxp cryoglobulin cultured cxc cxcl10 cxcl9 cxcr3 cxcr4 cyclooxygenase cyclophosphamide cyclosporin cyst cytokines cytoplasmic cytoskeleton derma development diabetes diabetic_nephropathy dialysis diazepam differentiation disease diseases dna dna-binding dose-response down-regulation drug duct dyspnea eicosapentaenoic empiric emt endocrine endocytosis endothelial_cell enzyme-linked epo eps er_stress escape_trial et-1 experimental expression factor factor-alpha factor-kappa factors failure fatty female fetuin-a fibrosis file-import-08-07-13 foam g12-g13-larg gain_of_function ganglia gdp gene genetic genetics gland glucose-6-phosphatase glycoproteins growth gsk3 gtp h haloperidol hba1c heart_failure hemodialysis hemorrhagic hepatic_fibrosis hepatocellular hepatocytes hitopathology hmgb1 ho-1 homing hormones humans hydrolases hyperkalaemia hyperlipidemias hypertension hypertrophy hypokalaemia hypotension i icr iddm idiopathic_glomerular_disease ii ikkbeta immunity immunosorbent immunosuppression inbred indication infection inflammation injections injury insulin insulin_resistance interferon interleukin-1 interleukin-6 interleukin-8 interstitial_nephritis intestinal intraperitoneal ir iron ischemiareperfusion islets ivig japan jewel jewels kdoqi kidney kidney_biopsy knockout kupffer langerhans leukocyte ligand ligands ligation line lipid lipids lipolysis lipopolysaccharides liver lna lorazepam lung macrophages magnetic male marrow matrix mechanism mediators medical_science mellitus membrane messenger metabolic metabolic_acidosis metabolic_syndrome metabolism metalloproteinase method mice middle mirna mn monoclonal monocyte monocytes movement mpa mpgn mrna mucosa mutant mutation myeloid ncrna necrosis neoplasms nephrology nephrosclerosis nephrotic_syndrome neutralization neutrophils nf-kappa nod nonesterified non-narcotic nuclear obese obesity ocular of osteoclast p38-mapk palmitic paracrine paradox pathology pd peptide peptides phosphoenolpyruvate phosphorylation physical_exam pkd1 placebo pnmrs podocyte polii ppar- primary_care prognosis progression proliferation propylene_glycol protein protein_c proteins proto-oncogene pth rank rapid_onset rats rct receptor receptors recombinant regeneration regulation regulatory relationship renal_failure renal_fibrosis renin repair reperfusion repressor research resistance review rho rifle risk risperidone rituximab rna rnai rock rosubastatin salicylate salt screening sdf-1 sedation sepsis shock signal signalling simvastatin sleleton smooth_muscle snail sonography spot_urine sprague-dawley stem_cell steroid_treatment strains syndrome techniques tests tetrachloride tgf-1 tgf-beta thyroglobulin thyroid time tissue tlr4 t-lymphocytes toll-like training transaminase transcription transducing transduction transfection transformation transforming transgenic transplantation transport triglycerides tubular tumor type ubiquitination upar up-regulation urine_culture uti uuo vegf vesicular visualizing vit_d_knockout western white women x y-27632