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xdeupi's switch [25 articles]

当前文献位于 xdeupi's 文献库 标签分类为 switch. You can also see everyone's switch.
  • Activation of the mu opioid receptor involves conformational rearrangements of multiple transmembrane domains.
    Biochemistry, Vol. 47, No. 40. (7 October 2008), pp. 10576-10586.
    by W Xu, A Sanz, L Pardo, LY Liu-Chen
    posted to switch opioid modeling cys_scanning activation by xdeupi on 2008-10-15 10:57:26 as **
  • G protein coupled receptor structure and activation.
    Biochim Biophys Acta, Vol. 1768, No. 4. (April 2007), pp. 794-807.
    by BK Kobilka
  • Multiple signaling states of G-protein-coupled receptors.
    Pharmacol Rev, Vol. 57, No. 2. (June 2005), pp. 147-161.
    by DM Perez, SS Karnik
  • Role of group-conserved residues in the helical core of beta2-adrenergic receptor.
    Proc Natl Acad Sci U S A, Vol. 104, No. 17. (24 April 2007), pp. 7027-7032.
    posted to activation agonist b2ar ser switch tm4 by xdeupi on 2007-04-26 12:27:17 as ** along with 1 group LabCompMed
  • Pharmacogenomic and structural analysis of constitutive g protein-coupled receptor activity.
    Annu Rev Pharmacol Toxicol, Vol. 47 (2007), pp. 53-87.
    by MJ Smit, HF Vischer, RA Bakker, A Jongejan, H Timmerman, L Pardo, R Leurs
  • Dosage-dependent switch from G protein-coupled to G protein-independent signaling by a GPCR
    The EMBO Journal, Vol. aop, No. current. (14 December 2006)
    by Yutong Sun, Jianyun Huang, Yang Xiang, Murat Bastepe, Harald Juppner, Brian K Kobilka, Jillian J Zhang, Xin-Yun Huang
  • Common structural requirements for heptahelical domain function in class A and class C GPCRS.
    J Biol Chem (19 February 2007)
    by Virginie Binet, Béatrice Duthey, Jennifer Lecaillon, Claire Vol, Julie Quoyer, Gilles Labesse, Jean-Philippe P Pin, Laurent Prézeau
    posted to activation class_c gaba gpcr switch by xdeupi on 2007-02-26 09:21:25 as ** along with 1 group LabCompMed
  • How a small change in retinal leads to G-protein activation: initial events suggested by molecular dynamics calculations.
    Proteins, Vol. 66, No. 3. (15 February 2007), pp. 559-574.
    by PS Crozier, MJ Stevens, TB Woolf
  • A change in conformational dynamics underlies the activation of Eph receptor tyrosine kinases
    The EMBO Journal, Vol. aop, No. current. (14 September 2006)
    by Silke Wiesner, Leanne E Wybenga-Groot, Neil Warner, Hong Lin, Tony Pawson, Julie D Forman-Kay, Frank Sicheri
  • dummy
  • The ring of the rhodopsin chromophore in a hydrophobic activation switch within the binding pocket.
    J Mol Biol, Vol. 343, No. 3. (22 October 2004), pp. 719-730.
    posted to activation nmr rhodopsin switch w648 by xdeupi on 2006-10-26 11:46:48 as **** along with 1 group LabCompMed
  • Functional selectivity and classical concepts of quantitative pharmacology.
    J Pharmacol Exp Ther (27 June 2006)
    by Jonathan D D Urban, William P P Clarke, Mark von Zastrow, David E E Nichols, Brian K K Kobilka, Harel Weinstein, Jonathan A A Javitch, Bryan L L Roth, Arthur Christopoulos, Patrick Sexton, Keith Miller, Michael Spedding, Richard B B Mailman
  • Metal Ion Site Engineering Indicates a Global Toggle Switch Model for Seven-transmembrane Receptor Activation.
    J Biol Chem, Vol. 281, No. 25. (23 June 2006), pp. 17337-17346.
    by CE Elling, TM Frimurer, LO Gerlach, R Jorgensen, B Holst, TW Schwartz
  • Picosecond dynamics of G-protein coupled receptor activation in rhodopsin from time-resolved UV resonance Raman spectroscopy.
    Biochemistry, Vol. 42, No. 18. (13 May 2003), pp. 5169-5175.
    by JE Kim, D Pan, RA Mathies
  • Orientation of aromatic residues in rhodopsin. Rotation of one tryptophan upon the meta I to meta II transition afer illumination.
    Photochem Photobiol, Vol. 30, No. 2. (August 1979), pp. 295-299.
    by M Chabre, J Breton
  • Molecular mechanism of 7TM receptor activation--a global toggle switch model.
    Annu Rev Pharmacol Toxicol, Vol. 46 (2006), pp. 481-519.
    by TW Schwartz, TM Frimurer, B Holst, MM Rosenkilde, CE Elling
  • Changes in interhelical hydrogen bonding upon rhodopsin activation.
    J Mol Biol, Vol. 347, No. 4. (8 April 2005), pp. 803-812.
    by AB Patel, E Crocker, PJ Reeves, EV Getmanova, M Eilers, HG Khorana, SO Smith
  • A GPCR that is not "DRY".
    Mol Pharmacol, Vol. 68, No. 1. (July 2005), pp. 1-3.
    by CA Flanagan
    posted to activation dry gpcr ionic switch tm3 by xdeupi on 2006-05-23 12:08:02 as **** along with 1 group LabCompMed
  • Role of the PAR1 Receptor 8th Helix in Signaling: THE 7-8-1 RECEPTOR ACTIVATION MECHANISM
    J. Biol. Chem., Vol. 281, No. 7. (17 February 2006), pp. 4109-4116.
    by Steven Swift, Andrew J Leger, Joyce Talavera, Lei Zhang, Andrew Bohm, Athan Kuliopulos
  • Electron crystallography reveals the structure of metarhodopsin I.
    EMBO J, Vol. 23, No. 18. (15 September 2004), pp. 3609-3620.
    by JJ Ruprecht, T Mielke, R Vogel, C Villa, GF Schertler
  • Evolutionary trace of G protein-coupled receptors reveals clusters of residues that determine global and class-specific functions.
    J Biol Chem, Vol. 279, No. 9. (27 February 2004), pp. 8126-8132.
    by S Madabushi, AK Gross, A Philippi, EC Meng, TG Wensel, O Lichtarge
  • Activation of the beta 2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6.
    J Biol Chem, Vol. 276, No. 31. (3 August 2001), pp. 29171-29177.
  • Beta2 adrenergic receptor activation. Modulation of the proline kink in transmembrane 6 by a rotamer toggle switch.
    J Biol Chem, Vol. 277, No. 43. (25 October 2002), pp. 40989-40996.
    by L Shi, G Liapakis, R Xu, F Guarnieri, JA Ballesteros, JA Javitch
  • An activation switch in the rhodopsin family of G protein-coupled receptors: the thyrotropin receptor.
    J Biol Chem, Vol. 280, No. 17. (29 April 2005), pp. 17135-17141.
    posted to activation n745 n749 switch thyrotropin by xdeupi on 2005-10-25 03:13:29 as read along with 1 group LabCompMed
  • Probing the beta2 adrenoceptor binding site with catechol reveals differences in binding and activation by agonists and partial agonists.
    J Biol Chem, Vol. 280, No. 23. (10 June 2005), pp. 22165-22171.
    by G Swaminath, X Deupi, TW Lee, W Zhu, FS Thian, TS Kobilka, B Kobilka
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