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xdeupi's gpcr [84 articles]

当前文献位于 xdeupi's 文献库 标签分类为 gpcr. You can also see everyone's gpcr.
  • Investigation of transmembrane proteins using a computational approach.
    BMC genomics, Vol. 9 Suppl 1 (2008)
    by JY Yang, MQ Yang, AK Dunker, Y Deng, X Huang
    posted to transmembrane theory structure membrane_proteins loops gpcr disorder by xdeupi on 2008-10-20 22:23:57 as **
  • Physiological relevance of GPCR oligomerization and its impact on drug discovery
    Drug Discovery Today (14 October 2008)
    by R Panetta, M Greenwood
    posted to review pharmacology ligands gpcr drug disease dimer by xdeupi on 2008-10-16 09:57:50 as **
  • The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist
    Science (2 October 2008), 1164772.
    by Veli-Pekka Jaakola, Mark T Griffith, Michael A Hanson, Vadim Cherezov, Ellen Y Chien, Robert J Lane, Adriaan P Ijzerman, Raymond C Stevens
    posted to xray structure ligands gpcr docking crystallography binding by xdeupi on 2008-10-15 10:02:26 as ** along with 1 person and 1 group cen4ik LabCompMed
  • Seven transmembrane receptors: a brief personal retrospective.
    Biochimica et biophysica acta, Vol. 1768, No. 4. (April 2007), pp. 748-755.
    by RJ Lefkowitz
    posted to review lmc_101 gpcr by xdeupi on 2008-09-02 11:50:30 as ** along with 1 person IrinaMoreira
  • Crystal structure of squid rhodopsin with intracellularly extended cytoplasmic region.
    The Journal of biological chemistry (6 May 2008)
    by Tatsuro Shimamura, Kenji Hiraki, Naoko Takahashi, Tetsuya Hori, Hideo Ago, Katsuyoshi Masuda, Koji Takio, Masaji Ishiguro, Masashi Miyano
    posted to crystallography cterm gpcr rhodopsin structure xray by xdeupi on 2008-05-13 16:19:24 as ** along with 1 group LabCompMed
  • Crystallizing thinking about the beta2-adrenergic receptor.
    Mol Pharmacol (31 January 2008)
    by Arun K K Shukla, Jin-Peng P Sun, Robert J J Lefkowitz
    posted to b2ar crystallography gpcr review by xdeupi on 2008-05-13 16:09:07 as ** along with 3 people agrossfield tkershaw merj
  • Mechanisms of Inter- and Intramolecular Communication in GPCRs and G Proteins
    J. Am. Chem. Soc. (12 March 2008)
    by F Raimondi, M Seeber, PG Debenedetti, F Fanelli
    posted to activation docking gpcr gproteins by xdeupi on 2008-05-03 17:09:50 as ** along with 1 person paulschlesinger
  • Stable Interactions Between the Transmembrane Domains of the Adenosine A2A Receptor.
    Protein science : a publication of the Protein Society (23 April 2008)
    by Damien Thevenin, Tzvetana Lazarova
    posted to folding gpcr structure transmembrane by xdeupi on 2008-04-28 11:00:29 as ** along with 1 person IrinaMoreira
  • The G protein-coupled receptor kinase (GRK) interactome: role of GRKs in GPCR regulation and signaling.
    Biochim Biophys Acta, Vol. 1768, No. 4. (April 2007), pp. 913-922.
    by C Ribas, P Penela, C Murga, A Salcedo, C García-Hoz, M Jurado-Pueyo, I Aymerich, F Mayor
    posted to activation arrestin gpcr grk by xdeupi on 2007-07-30 14:59:43 as ** along with 1 group LabCompMed
  • G-protein-coupled receptor signalling through protein networks.
    Biochem Soc Trans, Vol. 35, No. Pt 1. (February 2007), pp. 23-27.
    by AD Strosberg, C Nahmias
    posted to b2ar gpcr pharmacology review structure by xdeupi on 2007-06-29 21:10:57 as ** along with 1 group LabCompMed
  • Heterologous Expression of the Adenosine A1 Receptor in Transgenic Mouse Retina.
    Biochemistry (20 June 2007)
    by Ning Li, David Salom, Li Zhang, Tim Harris, Juan A Ballesteros, Marcin Golczak, Beata Jastrzebska, Krzysztof Palczewski, Carole Kurahara, Todd Juan, Steven Jordan, John A Salon
    posted to expression gpcr pharmacology by xdeupi on 2007-06-25 10:09:54 as ** along with 1 group LabCompMed
  • Structures and spectral signatures of protonated water networks in bacteriorhodopsin.
    Proc Natl Acad Sci U S A, Vol. 104, No. 17. (24 April 2007), pp. 6980-6985.
    by G Mathias, D Marx
    posted to activation gpcr protonation retinal_binding_proteins rhodopsin theory water by xdeupi on 2007-06-11 10:25:44 as *** along with 1 person and 1 group saravan LabCompMed
  • Constitutive activity and inverse agonism at the alpha1adrenoceptors.
    Biochem Pharmacol, Vol. 73, No. 8. (15 April 2007), pp. 1076-1083.
    by S Cotecchia
    posted to activation gpcr review by xdeupi on 2007-06-02 19:31:15 as ** along with 1 group LabCompMed
  • Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base
    BMC Bioinformatics, Vol. 8 (30 May 2007), 177.
    by Lucy Skrabanek, Marta Murcia, Michel Bouvier, Lakshmi Devi, Susan R George, Martin J Lohse, Graeme Milligan, Richard Neubig, Krzysztof Palczewski, Marc Parmentier, Jean-Philippe Pin, Gerrit Vriend, Jonathan A Javitch, Fabien Campagne, Marta Filizola
    posted to dimer gpcr review by xdeupi on 2007-06-02 19:25:57 as ** along with 1 group LabCompMed
  • Structure-function of alpha1-adrenergic receptors.
    Biochem Pharmacol, Vol. 73, No. 8. (15 April 2007), pp. 1051-1062.
    by DM Perez
    posted to activation gpcr review by xdeupi on 2007-06-02 19:21:05 as ** along with 1 group LabCompMed
  • G protein coupled receptor structure and activation.
    Biochim Biophys Acta, Vol. 1768, No. 4. (April 2007), pp. 794-807.
    by BK Kobilka
    posted to switch review lmc_101 gpcr b2ar activation by xdeupi on 2007-06-02 19:19:32 as ** along with 4 people and 2 groups jyuh Fritz merj adamsdi neurolit LabCompMed
  • Structural models of class a g protein-coupled receptors as a tool for drug design: insights on transmembrane bundle plasticity.
    Curr Top Med Chem, Vol. 7, No. 10. (2007), pp. 999-1006.
    by X Deupi Nicole Dölker María Luz López-Rodríguez Mercedes Campillo Juan A Ballesteros And Leonardo Pardo, N Dölker, ML López-Rodríguez, M Campillo, JA Ballesteros, L Pardo
    posted to binding gpcr modeling plasticity structure by xdeupi on 2007-05-28 08:51:54 as ** along with 1 group LabCompMed
  • The tachykinin tale: molecular recognition in a historical perspective.
    J Mol Recognit (20 April 2007)
    by Thomas Werge
    posted to gpcr neurokinin review by xdeupi on 2007-05-02 09:00:00 as ** along with 1 group LabCompMed
  • Multiple signaling states of G-protein-coupled receptors.
    Pharmacol Rev, Vol. 57, No. 2. (June 2005), pp. 147-161.
    by DM Perez, SS Karnik
    posted to activation agonist gpcr pharmacology review rhodopsin switch by xdeupi on 2007-04-26 14:57:25 as ***** along with 1 group LabCompMed
  • Helix packing moments reveal diversity and conservation in membrane protein structure.
    J Mol Biol, Vol. 337, No. 3. (26 March 2004), pp. 713-729.
    by W Liu, M Eilers, AB Patel, SO Smith
    posted to gpcr helix membrane_proteins rhodopsin sequence ser structure transmembrane by xdeupi on 2007-04-26 13:49:38 as ***** along with 1 group LabCompMed
  • Peptide design and structural characterization of a GPCR loop mimetic.
    Biopolymers (18 April 2007)
    by Truc-Chi T C Pham, Richard W W Kriwacki, Abby L L Parrill
    posted to gpcr loops modeling structure by xdeupi on 2007-04-23 10:24:23 as ** along with 1 group LabCompMed
  • Pharmacogenomic and structural analysis of constitutive g protein-coupled receptor activity.
    Annu Rev Pharmacol Toxicol, Vol. 47 (2007), pp. 53-87.
    by MJ Smit, HF Vischer, RA Bakker, A Jongejan, H Timmerman, L Pardo, R Leurs
    posted to activation disease gpcr modeling review structure switch by xdeupi on 2007-04-17 12:35:15 as ** along with 1 group LabCompMed
  • Synthesis of TOAC spin-labeled proteins and reconstitution in lipid membranes.
    Nat Protoc, Vol. 2, No. 1. (2007), pp. 42-49.
    by CB Karim, Z Zhang, DD Thomas
    posted to dynamics gpcr toac by xdeupi on 2007-04-10 19:30:43 as ** along with 1 group LabCompMed
  • Heterologous GPCR Expression: A Bottleneck to Obtaining Crystal Structures.
    Biotechnol Prog (31 March 2007)
    by Emily C McCusker, Steven E Bane, Michelle A O'malley, Anne S Robinson
    posted to crystallography gpcr review by xdeupi on 2007-04-10 19:18:56 as ** along with 1 group LabCompMed
  • Systematic analysis of the entire second extracellular loop of the V1a vasopressin receptor: Key residues, conserved throughout a G-protein-coupled receptor family, identified.
    J Biol Chem (2 April 2007)
    by Matthew Conner, Stuart R R Hawtin, John Simms, Denise L L Wootten, Zoe Lawson, Alex C C Conner, Rosemary A A Parslow, Mark Wheatley
    posted to activation amine binding ecl2 gpcr loops by xdeupi on 2007-04-10 18:59:06 as ***** along with 1 group LabCompMed
  • "Phenotypic" pharmacology: the influence of cellular environment on G protein-coupled receptor antagonist and inverse agonist pharmacology.
    Biochem Pharmacol, Vol. 73, No. 6. (15 March 2007), pp. 737-751.
    by CP Nelson, RA Challiss
    posted to agonist gpcr ligands pharmacology by xdeupi on 2007-04-10 18:54:26 as ** along with 1 person and 2 groups Fritz neurolit LabCompMed
  • Role of cholesterol in the function and organization of G-protein coupled receptors.
    Prog Lipid Res, Vol. 45, No. 4. (July 2006), pp. 295-333.
    by TJ Pucadyil, A Chattopadhyay
    posted to gpcr lipids membrane by xdeupi on 2007-04-10 18:46:46 as ** along with 1 person and 2 groups wsjames LabCompMed Oxford Virology
  • Inactive and active states and supramolecular organization of GPCRs: insights from computational modeling.
    J Comput Aided Mol Des, Vol. 20, No. 7-8. (g 2006), pp. 449-461.
    by F Fanelli, PG De Benedetti
    posted to gpcr modeling review by xdeupi on 2007-03-26 10:31:45 as ** along with 1 group LabCompMed
  • Method To Assess Packing Quality of Transmembrane alpha-Helices in Proteins. 1. Parametrization Using Structural Data.
    J Chem Inf Model (20 March 2007)
    by Anton O Chugunov, Valery N Novoseletsky, Dmitry E Nolde, Alexander S Arseniev, Roman G Efremov
    posted to gpcr membrane_proteins modeling structure by xdeupi on 2007-03-26 10:07:02 as ** along with 1 person and 1 group superpyrin LabCompMed
  • International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the Recognition and Nomenclature of G Protein-Coupled Receptor Heteromultimers.
    Pharmacol Rev, Vol. 59, No. 1. (March 2007), pp. 5-13.
    by JP Pin, R Neubig, M Bouvier, L Devi, M Filizola, JA Javitch, MJ Lohse, G Milligan, K Palczewski, M Parmentier, M Spedding
    posted to dimer gpcr review by xdeupi on 2007-03-12 14:26:45 as ** along with 1 group LabCompMed
  • Learning from the past: evolution of GPCR functions.
    Trends Pharmacol Sci (3 February 2007)
    by Torsten Schöneberg, Michael Hofreiter, Angela Schulz, Holger Römpler
    posted to evolution genome gpcr by xdeupi on 2007-02-27 11:08:24 as ** along with 1 group LabCompMed
  • Common structural requirements for heptahelical domain function in class A and class C GPCRS.
    J Biol Chem (19 February 2007)
    by Virginie Binet, Béatrice Duthey, Jennifer Lecaillon, Claire Vol, Julie Quoyer, Gilles Labesse, Jean-Philippe P Pin, Laurent Prézeau
    posted to activation class_c gaba gpcr switch by xdeupi on 2007-02-26 09:21:25 as ** along with 1 group LabCompMed
  • The first extracellular loop of the Saccharomyces cerevisiae GPCR STE2P undergoes a conformational change upon ligand binding.
    J Biol Chem (9 February 2007)
    by Melinda Hauser, Sarah Kauffman, Byung-Kwon K Lee, Fred Naider, Jeffrey M M Becker
    posted to activation binding gpcr loops by xdeupi on 2007-02-20 10:09:06 as ** along with 1 group LabCompMed
  • Initial sequencing and analysis of the human genome
    Nature, Vol. 409, No. 6822. (15 February 2001), pp. 860-921.
    by Michael J Morgan
    posted to gpcr genome by xdeupi on 2007-01-22 18:06:19 as ** along with 21 people and 3 groups reyez bozdagd cthachuk Cortel dragonrez jnemecek gg bicko Dax42 aprasad yas balajis dullhunk dgront djkt timflutre olympos nagendraproj incovoma yoanjacquemin brant Proteinkinases T_lab LabCompMed
  • Drugs, their targets and the nature and number of drug targets
    Nature Reviews Drug Discovery, Vol. 5, No. 10., pp. 821-834.
    by Peter Imming, Christian Sinning, Achim Meyer
    posted to review ligands gpcr genome drug by xdeupi on 2007-01-22 17:55:08 as ** along with 4 people and 1 group kuhn massivemayhem Ao_Li2007 yaredo LabCompMed
  • The sequence of the human genome.
    Science, Vol. 291, No. 5507. (16 February 2001), pp. 1304-1351.
    by JC Venter, MD Adams, EW Myers, PW Li, RJ Mural, GG Sutton, HO Smith, M Yandell, CA Evans, RA Holt, JD Gocayne, P Amanatides, RM Ballew, DH Huson, JR Wortman, Q Zhang, CD Kodira, XH Zheng, L Chen, M Skupski, G Subramanian, PD Thomas, J Zhang, GL Gabor Miklos, C Nelson, S Broder, AG Clark, J Nadeau, VA McKusick, N Zinder, AJ Levine, RJ Roberts, M Simon, C Slayman, M Hunkapiller, R Bolanos, A Delcher, I Dew, D Fasulo, M Flanigan, L Florea, A Halpern, S Hannenhalli, S Kravitz, S Levy, C Mobarry, K Reinert, K Remington, J Abu-Threideh, E Beasley, K Biddick, V Bonazzi, R Brandon, M Cargill, I Chandramouliswaran, R Charlab, K Chaturvedi, Z Deng, V Di Francesco, P Dunn, K Eilbeck, C Evangelista, AE Gabrielian, W Gan, W Ge, F Gong, Z Gu, P Guan, TJ Heiman, ME Higgins, RR Ji, Z Ke, KA Ketchum, Z Lai, Y Lei, Z Li, J Li, Y Liang, X Lin, F Lu, GV Merkulov, N Milshina, HM Moore, AK Naik, VA Narayan, B Neelam, D Nusskern, DB Rusch, S Salzberg, W Shao, B Shue, J Sun, Z Wang, A Wang, X Wang, J Wang, M Wei, R Wides, C Xiao, C Yan, A Yao, J Ye, M Zhan, W Zhang, H Zhang, Q Zhao, L Zheng, F Zhong, W Zhong, S Zhu, S Zhao, D Gilbert, S Baumhueter, G Spier, C Carter, A Cravchik, T Woodage, F Ali, H An, A Awe, D Baldwin, H Baden, M Barnstead, I Barrow, K Beeson, D Busam, A Carver, A Center, ML Cheng, L Curry, S Danaher, L Davenport, R Desilets, S Dietz, K Dodson, L Doup, S Ferriera, N Garg, A Gluecksmann, B Hart, J Haynes, C Haynes, C Heiner, S Hladun, D Hostin, J Houck, T Howland, C Ibegwam, J Johnson, F Kalush, L Kline, S Koduru, A Love, F Mann, D May, S McCawley, T McIntosh, I McMullen, M Moy, L Moy, B Murphy, K Nelson, C Pfannkoch, E Pratts, V Puri, H Qureshi, M Reardon, R Rodriguez, YH Rogers, D Romblad, B Ruhfel, R Scott, C Sitter, M Smallwood, E Stewart, R Strong, E Suh, R Thomas, NN Tint, S Tse, C Vech, G Wang, J Wetter, S Williams, M Williams, S Windsor, E Winn-Deen, K Wolfe, J Zaveri, K Zaveri, JF Abril, R Guigó, MJ Campbell, KV Sjolander, B Karlak, A Kejariwal, H Mi, B Lazareva, T Hatton, A Narechania, K Diemer, A Muruganujan, N Guo, S Sato, V Bafna, S Istrail, R Lippert, R Schwartz, B Walenz, S Yooseph, D Allen, A Basu, J Baxendale, L Blick, M Caminha, J Carnes-Stine, P Caulk, YH Chiang, M Coyne, C Dahlke, A Mays, M Dombroski, M Donnelly, D Ely, S Esparham, C Fosler, H Gire, S Glanowski, K Glasser, A Glodek, M Gorokhov, K Graham, B Gropman, M Harris, J Heil, S Henderson, J Hoover, D Jennings, C Jordan, J Jordan, J Kasha, L Kagan, C Kraft, A Levitsky, M Lewis, X Liu, J Lopez, D Ma, W Majoros, J McDaniel, S Murphy, M Newman, T Nguyen, N Nguyen, M Nodell, S Pan, J Peck, M Peterson, W Rowe, R Sanders, J Scott, M Simpson, T Smith, A Sprague, T Stockwell, R Turner, E Venter, M Wang, M Wen, D Wu, M Wu, A Xia, A Zandieh, X Zhu
    posted to gpcr genome by xdeupi on 2007-01-22 17:48:23 as ** along with 23 people and 3 groups frohike jo_davies reyez twenta aramata Cortel jwortman jnemecek bicko Dax42 yas balajis arcticrasta dgront olympos incovoma naegele mimulus_99 brant granujilla CitoJam renatomilani Neeperando Proteinkinases T_lab LabCompMed
  • G-protein coupled receptor structure.
    Biochim Biophys Acta (10 October 2006)
    by Philip L L Yeagle, Arlene D D Albert
    posted to activation gpcr review rhodopsin structure by xdeupi on 2006-11-17 20:57:15 as ***** along with 4 people and 1 group gcaltabiano merj superpyrin adamsdi LabCompMed
  • Dynamic models of G-protein coupled receptor dimers: indications of asymmetry in the rhodopsin dimer from molecular dynamics simulations in a POPC bilayer.
    J Comput Aided Mol Des (7 November 2006)
    by Marta Filizola, Simon X Wang, Harel Weinstein
    posted to activation dynamics gpcr lipids md membrane rhodopsin structure by xdeupi on 2006-11-14 16:42:29 as ** along with 1 group LabCompMed
  • Latest development in drug discovery on G protein-coupled receptors.
    Curr Protein Pept Sci, Vol. 7, No. 5. (October 2006), pp. 465-470.
    by K Lundstrom
    posted to drug gpcr review by xdeupi on 2006-11-04 12:42:42 as ** along with 1 person and 1 group denissohy LabCompMed
  • I want a new drug: G-protein-coupled receptors in drug development.
    Drug Discov Today, Vol. 11, No. 11-12. (June 2006), pp. 481-493.
    by S Schlyer, R Horuk
    posted to drug gpcr ligands pharmacology review by xdeupi on 2006-11-04 12:41:53 as ** along with 1 person and 1 group zimbo1 LabCompMed
  • dummy
    by Dummy
    posted to 5ht1a activation agonist amber amine arrestin b2ar bimane binding cam ccr5 channel chemokine chimera crystallography cterm cxcr1 d250 dimer disease drug dry dynamics ecl2 evolution expression fluorescence folding fret genome gly gpcr gproteins hbond helix helix8 histamine hormone icl3 imaging internalization ionic leukotriene lhr ligands lipids lock loops md membrane modeling mutation n745 n749 nmr no-tag npxxy nterm opioid pharmacology polymorphism pro-kink protonation review rhodopsin s542 sequence ser spin_labeling structure switch test thr thyrotropin tm2 tm3 tm5 tm6 tm7 toggle transmembrane trp txp w648 by xdeupi on 2006-10-30 12:30:16 as ** along with 2 people and 1 group jessicaopacic ivanrt LabCompMed
  • GRK specificity for beta -arrestin recruitment to the beta 2-adrenergic receptor revealed by fluorescence resonance energy transfer.
    J Biol Chem (10 May 2006)
    by Jonathan D D Violin, Xiu-Rong R Ren, Robert J J Lefkowitz
    posted to arrestin b2ar fret gpcr by xdeupi on 2006-09-23 11:20:25 as *** along with 1 person and 1 group tkershaw LabCompMed
  • Transmembrane signaling by G protein-coupled receptors.
    Methods Mol Biol, Vol. 332 (2006), pp. 3-49.
    by LM Luttrell
    posted to activation erc_grant gpcr review by xdeupi on 2006-09-05 11:46:39 as ** along with 1 person and 3 groups dchughes G4ID LabCompMed Genetics-of-Gambling
  • PDZ-domain arrays for identifying components of GPCR signaling complexes.
    Trends Pharmacol Sci (8 August 2006)
    by Peter Day, Brian Kobilka
    posted to activation gpcr by xdeupi on 2006-09-05 10:59:12 as ** along with 1 group LabCompMed
  • Structure and dynamics of dark-state bovine rhodopsin revealed by chemical cross-linking and high-resolution mass spectrometry.
    Protein Sci, Vol. 15, No. 6. (June 2006), pp. 1303-1317.
    by RB Jacobsen, KL Sale, MJ Ayson, P Novak, J Hong, P Lane, NL Wood, GH Kruppa, MM Young, JS Schoeniger
    posted to dynamics gpcr modeling rhodopsin structure by xdeupi on 2006-09-05 10:52:14 as ** along with 1 group LabCompMed
  • G proteins in drug screening: from analysis of receptor-G protein specificity to manipulation of GPCR-mediated signalling pathways.
    Curr Pharm Des, Vol. 12, No. 14. (2006), pp. 1703-1715.
    by E Kostenis
    posted to activation cterm drug ecl2 gpcr gproteins pharmacology by xdeupi on 2006-09-05 09:59:05 as **** along with 1 group LabCompMed
  • The three-dimensional structure of bovine rhodopsin determined by electron cryomicroscopy.
    J Biol Chem, Vol. 278, No. 50. (12 December 2003), pp. 50217-50225.
    by A Krebs, PC Edwards, C Villa, J Li, GF Schertler
    posted to crystallography gpcr membrane rhodopsin structure by xdeupi on 2006-07-25 15:17:32 as ** along with 1 group LabCompMed
  • A two-entropies analysis to identify functional positions in the transmembrane region of class A G protein-coupled receptors.
    Proteins, Vol. 63, No. 4. (1 June 2006), pp. 1018-1030.
    by K Ye, EW Lameijer, MW Beukers, AP Ijzerman
    posted to activation gpcr sequence transmembrane by xdeupi on 2006-07-24 10:21:33 as **** along with 2 people and 1 group cen4ik cat_worth LabCompMed
  • GPCR agonists and antagonists in the clinic.
    Med Chem, Vol. 1, No. 4. (July 2005), pp. 405-421.
    by JD Tyndall, R Sandilya
    posted to agonist drug gpcr ligands pharmacology by xdeupi on 2006-07-24 10:18:01 as ** along with 1 group LabCompMed
  • Improvements in G protein-coupled receptor purification yield light stable rhodopsin crystals.
    J Struct Biol (2 June 2006)
    by David Salom, Isolde Le Trong, Ehmke Pohl, Juan A A Ballesteros, Ronald E E Stenkamp, Krzysztof Palczewski, David T T Lodowski
    posted to activation crystallography gpcr rhodopsin by xdeupi on 2006-07-17 16:03:00 as read along with 1 group LabCompMed
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