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xdeupi's binding [34 articles]

当前文献位于 xdeupi's 文献库 标签分类为 binding. You can also see everyone's binding.
  • Functional role of the extracellular N-terminal domain of neuropeptide Y subfamily receptors in membrane integration and agonist-stimulated internalization.
    Cellular signalling (22 September 2008)
    by Diana Lindner, Cornelia Walther, Anja Tennemann, Annette G G Beck-Sickinger
    posted to tm1 nterm internalization binding activation by xdeupi on 2008-10-20 22:13:34 as **
  • Fluorescent GPCR ligands as new tools in pharmacology.
    Current medicinal chemistry, Vol. 15, No. 21. (2008), pp. 2132-2143.
    by K Kuder, K Kieć-Kononowicz
    posted to ligands imaging fluorescence drug binding agonist activation by xdeupi on 2008-10-15 10:30:17 as **
  • The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist
    Science (2 October 2008), 1164772.
    by Veli-Pekka Jaakola, Mark T Griffith, Michael A Hanson, Vadim Cherezov, Ellen Y Chien, Robert J Lane, Adriaan P Ijzerman, Raymond C Stevens
    posted to xray structure ligands gpcr docking crystallography binding by xdeupi on 2008-10-15 10:02:26 as ** along with 1 person and 1 group cen4ik LabCompMed
  • Structure of a β1-adrenergic G-protein-coupled receptor
    Nature (25 June 2008)
    by Tony Warne, Maria J Serrano-Vega, Jillian G Baker, Rouslan Moukhametzianov, Patricia C Edwards, Richard Henderson, Andrew GW Leslie, Christopher G Tate, Gebhard FX Schertler
    posted to xray structure ligands drug docking binding b2ar by xdeupi on 2008-09-16 10:15:17 as ** along with 2 people and 2 groups merj TonyIvetac LabCompMed McCammon
  • Recruitment of beta-arrestin2 to the dopamine D2 receptor: Insights into anti-psychotic and anti-parkinsonian drug receptor signaling.
    Neuropharmacology (8 April 2008)
    by Ib V V Klewe, Søren M M Nielsen, Louise Tarpø, Eneko Urizar, Concetta Dipace, Jonathan A A Javitch, Ulrik Gether, Jan Egebjerg, Kenneth V V Christensen
    posted to activation active-state agonist arrestin biased_agonism binding disease fluorescence imaging internalization pharmacology by xdeupi on 2008-05-13 16:24:49 as **
  • Chemogenomic approaches to rational drug design
    Br J Pharmacol, Vol. 152, No. 1. (29 May 2007), pp. 38-52.
    by D Rognan
    posted to agonist binding drug ligands pharmacology priviledged_structures by xdeupi on 2008-03-28 15:54:47 as ** along with 4 people and 3 groups jmrivort jerome_ucsf_slb jyuh tjimenez LabCompMed G-quadruplex Supramolecular
  • notes Chloroethylclonidine and 2-aminoethyl methanethiosulfonate recognize two different conformations of the human alpha(2A)-adrenergic receptor.
    J Biol Chem, Vol. 274, No. 31. (30 July 1999), pp. 21867-21872.
    by A Marjamäki, H Frang, M Pihlavisto, AM Hoffrén, T Salminen, MS Johnson, J Kallio, JA Javitch, M Scheinin
    posted to activation binding cys_scanning drug ligands tm5 by xdeupi on 2008-03-07 15:14:37 as ** along with 1 group LabCompMed
  • Identification of the Binding Sites of the SR49059 Nonpeptide Antagonist into the V1a Vasopressin Receptor Using Sulfydryl-reactive Ligands and Cysteine Mutants as Chemical Sensors
    J. Biol. Chem., Vol. 278, No. 41. (10 October 2003), pp. 40010-40019.
    by Chouaib Tahtaoui, Marie-Noelle Balestre, Philippe Klotz, Didier Rognan, Claude Barberis, Bernard Mouillac, Marcel Hibert
    posted to binding cys_scanning peptide vasopressin by xdeupi on 2008-02-28 16:16:02 as **
  • Critical role for the second extracellular loop in the binding of both orthosteric and allosteric G protein-coupled receptor ligands.
    J Biol Chem (25 June 2007)
    by Vimesh A A Avlani, Karen J J Gregory, Craig J J Morton, Michael W W Parker, Patrick M M Sexton, Arthur Christopoulos
    posted to activation binding ecl2 ligands loops structure by xdeupi on 2007-06-29 21:12:42 as ** along with 1 group LabCompMed
  • Structural models of class a g protein-coupled receptors as a tool for drug design: insights on transmembrane bundle plasticity.
    Curr Top Med Chem, Vol. 7, No. 10. (2007), pp. 999-1006.
    by X Deupi Nicole Dölker María Luz López-Rodríguez Mercedes Campillo Juan A Ballesteros And Leonardo Pardo, N Dölker, ML López-Rodríguez, M Campillo, JA Ballesteros, L Pardo
    posted to binding gpcr modeling plasticity structure by xdeupi on 2007-05-28 08:51:54 as ** along with 1 group LabCompMed
  • Chromophore Channeling in the G-Protein Coupled Receptor Rhodopsin.
    J Am Chem Soc (15 May 2007)
    by Ting Wang, Yong Duan
    posted to activation agonist amber binding ligands md modeling rhodopsin by xdeupi on 2007-05-21 10:04:04 as ***** along with 1 group LabCompMed
  • Multiple residues in the second extracellular loop are critical for M3 muscarinic acetylcholine receptor activation.
    J Biol Chem, Vol. 282, No. 10. (9 March 2007), pp. 7385-7396.
    by M Scarselli, B Li, SK Kim, J Wess
    posted to activation amine binding ecl2 loops mutation by xdeupi on 2007-04-23 10:28:29 as **** along with 1 person and 1 group IrinaMoreira LabCompMed
  • Systematic analysis of the entire second extracellular loop of the V1a vasopressin receptor: Key residues, conserved throughout a G-protein-coupled receptor family, identified.
    J Biol Chem (2 April 2007)
    by Matthew Conner, Stuart R R Hawtin, John Simms, Denise L L Wootten, Zoe Lawson, Alex C C Conner, Rosemary A A Parslow, Mark Wheatley
    posted to activation amine binding ecl2 gpcr loops by xdeupi on 2007-04-10 18:59:06 as ***** along with 1 group LabCompMed
  • The first extracellular loop of the Saccharomyces cerevisiae GPCR STE2P undergoes a conformational change upon ligand binding.
    J Biol Chem (9 February 2007)
    by Melinda Hauser, Sarah Kauffman, Byung-Kwon K Lee, Fred Naider, Jeffrey M M Becker
    posted to activation binding gpcr loops by xdeupi on 2007-02-20 10:09:06 as ** along with 1 group LabCompMed
  • Identification of an agonist-induced conformational change occurring adjacent to the ligand-binding pocket of the M(3) muscarinic acetylcholine receptor.
    J Biol Chem, Vol. 280, No. 41. (14 October 2005), pp. 34849-34858.
    by SJ Han, FF Hamdan, SK Kim, KA Jacobson, LM Bloodworth, B Li, J Wess
    posted to ligands cation-pi binding agonist by xdeupi on 2007-01-15 16:08:15 as ** along with 1 group LabCompMed
  • Cation-pi interactions in chemistry and biology: a new view of benzene, Phe, Tyr, and Trp.
    Science, Vol. 271, No. 5246. (12 January 1996), pp. 163-168.
    by DA Dougherty
    posted to trp cation-pi binding by xdeupi on 2007-01-12 17:18:14 as ** along with 4 people and 1 group medic0747 netterpaladin superpyrin viktor21614 LabCompMed
  • The Cationminus signpi Interaction.
    Chem Rev, Vol. 97, No. 5. (5 August 1997), pp. 1303-1324.
    by Jennifer C Ma, Dennis A Dougherty
    posted to trp ligands histamine cation-pi binding b2ar by xdeupi on 2007-01-11 14:28:54 as ** along with 1 group LabCompMed
  • GluVII:06--a highly conserved and selective anchor point for non-peptide ligands in chemokine receptors.
    Curr Top Med Chem, Vol. 6, No. 13. (2006), pp. 1319-1333.
    by MM Rosenkilde, TW Schwartz
    posted to modeling ligands ionic chemokine binding agonist by xdeupi on 2007-01-10 14:45:13 as ** along with 1 group LabCompMed
  • dummy
    by Dummy
    posted to 5ht1a activation agonist amber amine arrestin b2ar bimane binding cam ccr5 channel chemokine chimera crystallography cterm cxcr1 d250 dimer disease drug dry dynamics ecl2 evolution expression fluorescence folding fret genome gly gpcr gproteins hbond helix helix8 histamine hormone icl3 imaging internalization ionic leukotriene lhr ligands lipids lock loops md membrane modeling mutation n745 n749 nmr no-tag npxxy nterm opioid pharmacology polymorphism pro-kink protonation review rhodopsin s542 sequence ser spin_labeling structure switch test thr thyrotropin tm2 tm3 tm5 tm6 tm7 toggle transmembrane trp txp w648 by xdeupi on 2006-10-30 12:30:16 as ** along with 2 people and 1 group jessicaopacic ivanrt LabCompMed
  • Modeling and active site refinement for G protein-coupled receptors: application to the beta-2 adrenergic receptor.
    J Comput Aided Mol Des (13 October 2006)
    by Stanley R Krystek, S R Kimura, Andrew J Tebben
    posted to b2ar binding drug ligands modeling pharmacology by xdeupi on 2006-10-27 09:43:03 as ** along with 1 person and 1 group daevans LabCompMed
  • Novel mutants of the human beta1-adrenergic receptor reveal amino acids relevant for receptor activation.
    J Biol Chem, Vol. 281, No. 26. (30 June 2006), pp. 18120-18125.
    by B Behr, C Hoffmann, G Ottolina, KN Klotz
    posted to activation agonist b2ar binding drug ligands modeling mutation pharmacology structure by xdeupi on 2006-09-05 11:05:20 as *** along with 1 group LabCompMed
  • Data-Driven Analysis in Drug Discovery
    Journal of Receptors and Signal Transduction, Vol. 26, No. 4. (August 2006), pp. 299-327.
    by Terry Kenakin
    posted to agonist binding drug ligands pharmacology by xdeupi on 2006-07-17 16:28:05 as **** along with 1 group LabCompMed
  • Changes in interhelical hydrogen bonding upon rhodopsin activation.
    J Mol Biol, Vol. 347, No. 4. (8 April 2005), pp. 803-812.
    by AB Patel, E Crocker, PJ Reeves, EV Getmanova, M Eilers, HG Khorana, SO Smith
    posted to activation b2ar binding hbond helix ligands nmr pro-kink rhodopsin ser structure switch tm5 tm6 toggle by xdeupi on 2006-06-01 13:51:11 as read along with 1 group LabCompMed
  • Role of the retinal hydrogen bond network in rhodopsin Schiff base stability and hydrolysis.
    J Biol Chem, Vol. 279, No. 53. (31 December 2004), pp. 55886-55894.
    by JM Janz, DL Farrens
    posted to activation binding rhodopsin by xdeupi on 2006-05-29 11:58:42 as **** along with 1 group LabCompMed
  • Molecular evolution of adrenoceptors and dopamine receptors: implications for the binding of catecholamines.
    J Med Chem, Vol. 49, No. 5. (9 March 2006), pp. 1706-1719.
    by H Xhaard, VV Rantanen, T Nyrönen, MS Johnson
    posted to agonist b2ar binding gpcr ligands modeling by xdeupi on 2006-03-06 10:11:30 as **** along with 1 group LabCompMed
  • A chemogenomic analysis of the transmembrane binding cavity of human G-protein-coupled receptors.
    Proteins, Vol. 62, No. 2. (1 February 2006), pp. 509-538.
    by JS Surgand, J Rodrigo, E Kellenberger, D Rognan
    posted to binding gpcr ligands transmembrane by xdeupi on 2006-03-01 16:33:01 as ***** along with 1 person and 1 group naweill LabCompMed
  • Principal pathway coupling agonist binding to channel gating in nicotinic receptors
    Nature, Vol. 438, No. 7065. (10 November 2005), pp. 243-247.
    by Won Y Lee, Steven M Sine
    posted to activation agonist binding channel ser by xdeupi on 2006-01-27 12:32:01 as ** along with 1 person and 3 groups barry structural_bioinformatics Bioinformatics LabCompMed
  • Sequential binding of agonists to the beta2 adrenoceptor. Kinetic evidence for intermediate conformational states.
    J Biol Chem, Vol. 279, No. 1. (2 January 2004), pp. 686-691.
    by G Swaminath, Y Xiang, TW Lee, J Steenhuis, C Parnot, BK Kobilka
    posted to activation agonist b2ar binding ligands tm6 by xdeupi on 2005-12-16 10:19:18 as read along with 1 person and 1 group jddowney LabCompMed
  • Agonist binding: a multistep process.
    Mol Pharmacol, Vol. 65, No. 5. (May 2004), pp. 1060-1062.
    by B Kobilka
    posted to activation agonist b2ar binding gpcr by xdeupi on 2005-11-02 22:50:37 as ** along with 1 group LabCompMed
  • Evolutionary trace of G protein-coupled receptors reveals clusters of residues that determine global and class-specific functions.
    J Biol Chem, Vol. 279, No. 9. (27 February 2004), pp. 8126-8132.
    by S Madabushi, AK Gross, A Philippi, EC Meng, TG Wensel, O Lichtarge
    posted to activation binding gpcr sequence switch by xdeupi on 2005-11-01 20:03:29 as read along with 2 people and 1 group gbart sriram_s LabCompMed
  • Possible role of the 11-cis-retinyl conformation in controlling the dual decay processes of excited rhodopsin.
    Proc Natl Acad Sci U S A, Vol. 102, No. 31. (2 August 2005), pp. 10783-10787.
    by RS Liu, GS Hammond, T Mirzadegan
    posted to activation binding gpcr rhodopsin by xdeupi on 2005-11-01 19:48:57 as *** along with 1 group LabCompMed
  • Linking agonist binding to histamine H1 receptor activation
    Nat Chem Biol, Vol. 1, No. 2. (July 2005), pp. 98-103.
    by Aldo Jongejan, Martijn Bruysters, Juan A Ballesteros, Eric Haaksma, Remko A Bakker, Leonardo Pardo, Rob Leurs
    posted to activation agonist binding histamine n745 npxxy by xdeupi on 2005-11-01 01:19:58 as read along with 1 group LabCompMed
  • notes The forgotten serine. A critical role for Ser-2035.42 in ligand binding to and activation of the beta 2-adrenergic receptor.
    J Biol Chem, Vol. 275, No. 48. (1 December 2000), pp. 37779-37788.
    by G Liapakis, JA Ballesteros, S Papachristou, WC Chan, X Chen, JA Javitch
    posted to activation agonist b2ar binding s542 ser tm5 by xdeupi on 2005-11-01 01:02:07 as ** along with 1 group LabCompMed
  • The binding site of aminergic G protein-coupled receptors: the transmembrane segments and second extracellular loop.
    Annu Rev Pharmacol Toxicol, Vol. 42 (2002), pp. 437-467.
    by L Shi, JA Javitch
    posted to agonist binding ecl2 gpcr helix loops transmembrane by xdeupi on 2005-11-01 01:00:19 as ** along with 1 person and 1 group IrinaMoreira LabCompMed
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