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xdeupi's activation [125 articles]

当前文献位于 xdeupi's 文献库 标签分类为 activation. You can also see everyone's activation.
  • Functional role of the extracellular N-terminal domain of neuropeptide Y subfamily receptors in membrane integration and agonist-stimulated internalization.
    Cellular signalling (22 September 2008)
    by Diana Lindner, Cornelia Walther, Anja Tennemann, Annette G G Beck-Sickinger
    posted to tm1 nterm internalization binding activation by xdeupi on 2008-10-20 22:13:34 as **
  • Activation of the mu opioid receptor involves conformational rearrangements of multiple transmembrane domains.
    Biochemistry, Vol. 47, No. 40. (7 October 2008), pp. 10576-10586.
    by W Xu, A Sanz, L Pardo, LY Liu-Chen
    posted to switch opioid modeling cys_scanning activation by xdeupi on 2008-10-15 10:57:26 as **
  • Accelerated Dephosphorylation of the beta2-Adrenergic Receptor by Mutation of the C-Terminal Lysines: Effects on Ubiquitination, Intracellular Trafficking, and Degradation.
    Biochemistry (9 October 2008)
    by Wei Liang, Quang Hoang, Richard B Clark, Peter H Fishman
    posted to internalization grk activation by xdeupi on 2008-10-15 10:51:58 as **
  • Fluorescent GPCR ligands as new tools in pharmacology.
    Current medicinal chemistry, Vol. 15, No. 21. (2008), pp. 2132-2143.
    by K Kuder, K Kieć-Kononowicz
    posted to ligands imaging fluorescence drug binding agonist activation by xdeupi on 2008-10-15 10:30:17 as **
  • Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin.
    Science (New York, N.Y.), Vol. 274, No. 5288. (1 November 1996), pp. 768-770.
    by DL Farrens, C Altenbach, K Yang, WL Hubbell, HG Khorana
    posted to activation rhodopsin tm6 by xdeupi on 2008-08-08 19:00:11 as ** along with 1 group LabCompMed
  • Proline-induced distortions of transmembrane helices.
    J Mol Biol, Vol. 323, No. 5. (8 November 2002), pp. 951-960.
    by FS Cordes, JN Bright, MS Sansom
    posted to activation helix membrane_proteins pro-kink structure theory transmembrane by xdeupi on 2008-05-27 11:58:27 as ** along with 1 person thaliana
  • Recruitment of beta-arrestin2 to the dopamine D2 receptor: Insights into anti-psychotic and anti-parkinsonian drug receptor signaling.
    Neuropharmacology (8 April 2008)
    by Ib V V Klewe, Søren M M Nielsen, Louise Tarpø, Eneko Urizar, Concetta Dipace, Jonathan A A Javitch, Ulrik Gether, Jan Egebjerg, Kenneth V V Christensen
    posted to activation active-state agonist arrestin biased_agonism binding disease fluorescence imaging internalization pharmacology by xdeupi on 2008-05-13 16:24:49 as **
  • Mechanisms of Inter- and Intramolecular Communication in GPCRs and G Proteins
    J. Am. Chem. Soc. (12 March 2008)
    by F Raimondi, M Seeber, PG Debenedetti, F Fanelli
    posted to activation docking gpcr gproteins by xdeupi on 2008-05-03 17:09:50 as ** along with 1 person paulschlesinger
  • The specificity of binding of glycoprotein hormones to their receptors.
    Cellular and molecular life sciences : CMLS (26 April 2008)
    by G Caltabiano, M Campillo, A De Leener, G Smits, G Vassart, S Costagliola, L Pardo
    posted to activation hormone modeling thyrotropin by xdeupi on 2008-05-03 17:06:33 as ** along with 1 group LabCompMed
  • Efficient coupling of transducin to monomeric rhodopsin in a phospholipid bilayer.
    J Biol Chem (22 November 2007)
    by Matthew R R Whorton, Beata Jastrzebska, Paul S-H S Park, Dimitrios Fotiadis, Andreas Engel, Krzysztof Palczewski, Roger K K Sunahara
    posted to activation dimer gproteins rhodopsin by xdeupi on 2008-03-12 17:12:36 as ** along with 1 person and 1 group gcaltabiano LabCompMed
  • Mapping of contact sites in complex formation between transducin and light-activated rhodopsin by covalent crosslinking: use of a photoactivatable reagent.
    Proc Natl Acad Sci U S A, Vol. 98, No. 9. (24 April 2001), pp. 4877-4882.
    by K Cai, Y Itoh, HG Khorana
    posted to activation active-state gproteins icl3 rhodopsin by xdeupi on 2008-03-12 15:47:55 as ** along with 1 person IrinaMoreira
  • Heterotrimeric G protein activation by G-protein-coupled receptors.
    Nat Rev Mol Cell Biol (28 November 2007)
    by William M M Oldham, Heidi E E Hamm
    posted to activation erc_grant gproteins rhodopsin by xdeupi on 2008-03-11 14:30:28 as ** along with 4 people and 2 groups dchughes Fritz mingzhi laurabailey neurolit LabCompMed
  • notes Chloroethylclonidine and 2-aminoethyl methanethiosulfonate recognize two different conformations of the human alpha(2A)-adrenergic receptor.
    J Biol Chem, Vol. 274, No. 31. (30 July 1999), pp. 21867-21872.
    by A Marjamäki, H Frang, M Pihlavisto, AM Hoffrén, T Salminen, MS Johnson, J Kallio, JA Javitch, M Scheinin
    posted to activation binding cys_scanning drug ligands tm5 by xdeupi on 2008-03-07 15:14:37 as ** along with 1 group LabCompMed
  • Transducin activation by nanoscale lipid bilayers containing one and two rhodopsins.
    J Biol Chem, Vol. 282, No. 20. (18 May 2007), pp. 14875-14881.
    by TH Bayburt, AJ Leitz, G Xie, DD Oprian, SG Sligar
    posted to activation dimer lipids rhodopsin by xdeupi on 2008-02-27 11:06:04 as ***
  • beta-Arrestin-biased Agonism at the beta2-Adrenergic Receptor.
    J Biol Chem, Vol. 283, No. 9. (29 February 2008), pp. 5669-5676.
    by MT Drake, JD Violin, EJ Whalen, JW Wisler, SK Shenoy, RJ Lefkowitz
    posted to activation agonist arrestin b2ar biased_agonism drug gproteins imaging internalization ligands pharmacology by xdeupi on 2008-02-27 10:39:07 as *** along with 1 group LabCompMed
  • Chemistry. Following the flow of energy in biomolecules.
    Science, Vol. 310, No. 5750. (11 November 2005), pp. 980-982.
    by PM Champion
    posted to activation retinal review rhodopsin by xdeupi on 2007-07-30 17:02:29 as **** along with 1 group LabCompMed
  • Proton movement and photointermediate kinetics in rhodopsin mutants.
    Biochemistry, Vol. 45, No. 17. (2 May 2006), pp. 5430-5439.
    by JW Lewis, I Szundi, MA Kazmi, TP Sakmar, DS Kliger
    posted to activation protonation rhodopsin by xdeupi on 2007-07-30 17:00:28 as ** along with 1 group LabCompMed
  • Primary photoprocess in vision: minimal motion to reach the photo- and bathorhodopsin intermediates.
    J Phys Chem B, Vol. 109, No. 18. (12 May 2005), pp. 9104-9110.
    by F Blomgren, S Larsson
    posted to activation retinal rhodopsin theory by xdeupi on 2007-07-30 16:59:24 as ** along with 1 group LabCompMed
  • Photoisomerization mechanism of rhodopsin and 9-cis-rhodopsin revealed by x-ray crystallography.
    Biophys J, Vol. 92, No. 12. (15 June 2007)
    by H Nakamichi, V Buss, T Okada
    posted to activation retinal rhodopsin by xdeupi on 2007-07-30 16:57:47 as ** along with 1 group LabCompMed
  • Coupling of retinal isomerization to the activation of rhodopsin
    PNAS, Vol. 101, No. 27. (6 July 2004), pp. 10048-10053.
    by Ashish B Patel, Evan Crocker, Markus Eilers, Amiram Hirshfeld, Mordechai Sheves, Steven O Smith
    posted to activation active-state nmr retinal rhodopsin by xdeupi on 2007-07-30 15:16:18 as ** along with 1 group LabCompMed
  • The G protein-coupled receptor kinase (GRK) interactome: role of GRKs in GPCR regulation and signaling.
    Biochim Biophys Acta, Vol. 1768, No. 4. (April 2007), pp. 913-922.
    by C Ribas, P Penela, C Murga, A Salcedo, C García-Hoz, M Jurado-Pueyo, I Aymerich, F Mayor
    posted to activation arrestin gpcr grk by xdeupi on 2007-07-30 14:59:43 as ** along with 1 group LabCompMed
  • Critical role for the second extracellular loop in the binding of both orthosteric and allosteric G protein-coupled receptor ligands.
    J Biol Chem (25 June 2007)
    by Vimesh A A Avlani, Karen J J Gregory, Craig J J Morton, Michael W W Parker, Patrick M M Sexton, Arthur Christopoulos
    posted to activation binding ecl2 ligands loops structure by xdeupi on 2007-06-29 21:12:42 as ** along with 1 group LabCompMed
  • Structures and spectral signatures of protonated water networks in bacteriorhodopsin.
    Proc Natl Acad Sci U S A, Vol. 104, No. 17. (24 April 2007), pp. 6980-6985.
    by G Mathias, D Marx
    posted to activation gpcr protonation retinal_binding_proteins rhodopsin theory water by xdeupi on 2007-06-11 10:25:44 as *** along with 1 person and 1 group saravan LabCompMed
  • Mapping allosteric connections from the receptor to the nucleotide-binding pocket of heterotrimeric G proteins.
    Proc Natl Acad Sci U S A (26 April 2007)
    by William M M Oldham, Ned Van Eps, Anita M M Preininger, Wayne L L Hubbell, Heidi E E Hamm
    posted to activation cterm gproteins rhodopsin by xdeupi on 2007-06-11 10:14:49 as ** along with 2 people and 1 group laurabailey choonpeng LabCompMed
  • Linkage between the intramembrane H-bond network around aspartic acid 83 and the cytosolic environment of helix 8 in photoactivated rhodopsin.
    J Mol Biol, Vol. 366, No. 4. (2 March 2007), pp. 1129-1141.
    by N Lehmann, U Alexiev, K Fahmy
    posted to activation d250 fluorescence npxxy rhodopsin by xdeupi on 2007-06-05 15:58:33 as ***** along with 1 group LabCompMed
  • Constitutive activity and inverse agonism at the alpha1adrenoceptors.
    Biochem Pharmacol, Vol. 73, No. 8. (15 April 2007), pp. 1076-1083.
    by S Cotecchia
    posted to activation gpcr review by xdeupi on 2007-06-02 19:31:15 as ** along with 1 group LabCompMed
  • Real-time analysis of agonist-induced activation of protease-activated receptor 1/Galphai1 protein complex measured by bioluminescence resonance energy transfer in living cells.
    Mol Pharmacol, Vol. 71, No. 5. (May 2007), pp. 1329-1340.
    by MA Ayoub, D Maurel, V Binet, M Fink, L Prézeau, H Ansanay, JP Pin
    posted to activation fret by xdeupi on 2007-06-02 19:29:56 as ** along with 1 group LabCompMed
  • Structure-function of alpha1-adrenergic receptors.
    Biochem Pharmacol, Vol. 73, No. 8. (15 April 2007), pp. 1051-1062.
    by DM Perez
    posted to activation gpcr review by xdeupi on 2007-06-02 19:21:05 as ** along with 1 group LabCompMed
  • G protein coupled receptor structure and activation.
    Biochim Biophys Acta, Vol. 1768, No. 4. (April 2007), pp. 794-807.
    by BK Kobilka
    posted to switch review lmc_101 gpcr b2ar activation by xdeupi on 2007-06-02 19:19:32 as ** along with 4 people and 2 groups jyuh Fritz merj adamsdi neurolit LabCompMed
  • Chromophore Channeling in the G-Protein Coupled Receptor Rhodopsin.
    J Am Chem Soc (15 May 2007)
    by Ting Wang, Yong Duan
    posted to activation agonist amber binding ligands md modeling rhodopsin by xdeupi on 2007-05-21 10:04:04 as ***** along with 1 group LabCompMed
  • Protein flexibility using constraints from molecular dynamics simulations.
    Phys Biol, Vol. 2, No. 4. (November 2005)
    by T Mamonova, B Hespenheide, R Straub, MF Thorpe, M Kurnikova
    posted to activation dynamics flexibility md by xdeupi on 2007-05-21 09:38:21 as ** along with 3 people and 1 group lna LamBras higueruelo LabCompMed
  • A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein.
    Proc Natl Acad Sci U S A (23 April 2007)
    by Matthew R R Whorton, Michael P P Bokoch, Søren G F G Rasmussen, Bo Huang, Richard N N Zare, Brian Kobilka, Roger K K Sunahara
    posted to activation b2ar dimer by xdeupi on 2007-05-02 09:04:56 as ** along with 1 group LabCompMed
  • Multiple signaling states of G-protein-coupled receptors.
    Pharmacol Rev, Vol. 57, No. 2. (June 2005), pp. 147-161.
    by DM Perez, SS Karnik
    posted to activation agonist gpcr pharmacology review rhodopsin switch by xdeupi on 2007-04-26 14:57:25 as ***** along with 1 group LabCompMed
  • Role of group-conserved residues in the helical core of beta2-adrenergic receptor.
    Proc Natl Acad Sci U S A, Vol. 104, No. 17. (24 April 2007), pp. 7027-7032.
    by P Chelikani, V Hornak, M Eilers, PJ Reeves, SO Smith, UL Rajbhandary, HG Khorana
    posted to activation agonist b2ar ser switch tm4 by xdeupi on 2007-04-26 12:27:17 as ** along with 1 group LabCompMed
  • Multiple residues in the second extracellular loop are critical for M3 muscarinic acetylcholine receptor activation.
    J Biol Chem, Vol. 282, No. 10. (9 March 2007), pp. 7385-7396.
    by M Scarselli, B Li, SK Kim, J Wess
    posted to activation amine binding ecl2 loops mutation by xdeupi on 2007-04-23 10:28:29 as **** along with 1 person and 1 group IrinaMoreira LabCompMed
  • Pharmacogenomic and structural analysis of constitutive g protein-coupled receptor activity.
    Annu Rev Pharmacol Toxicol, Vol. 47 (2007), pp. 53-87.
    by MJ Smit, HF Vischer, RA Bakker, A Jongejan, H Timmerman, L Pardo, R Leurs
    posted to activation disease gpcr modeling review structure switch by xdeupi on 2007-04-17 12:35:15 as ** along with 1 group LabCompMed
  • Systematic analysis of the entire second extracellular loop of the V1a vasopressin receptor: Key residues, conserved throughout a G-protein-coupled receptor family, identified.
    J Biol Chem (2 April 2007)
    by Matthew Conner, Stuart R R Hawtin, John Simms, Denise L L Wootten, Zoe Lawson, Alex C C Conner, Rosemary A A Parslow, Mark Wheatley
    posted to activation amine binding ecl2 gpcr loops by xdeupi on 2007-04-10 18:59:06 as ***** along with 1 group LabCompMed
  • Bioluminescence resonance energy transfer as a screening assay: Focus on partial and inverse agonism.
    J Biomol Screen, Vol. 12, No. 1. (February 2007), pp. 41-49.
    by L Elster, C Elling, A Heding
    posted to activation agonist b2ar fret ligands by xdeupi on 2007-04-10 18:50:15 as ** along with 1 group LabCompMed
  • Rhodopsin activation exposes a key hydrophobic binding site for the transducin alpha-subunit C terminus.
    J Biol Chem, Vol. 279, No. 28. (9 July 2004), pp. 29767-29773.
    by JM Janz, DL Farrens
    posted to activation bimane fluorescence rhodopsin tm6 by xdeupi on 2007-04-04 18:32:56 as ** along with 1 person and 1 group IrinaMoreira LabCompMed
  • Modeling activated states of GPCRs: the rhodopsin template.
    J Comput Aided Mol Des, Vol. 20, No. 7-8. (g 2006), pp. 437-448.
    by MY Niv, L Skrabanek, M Filizola, H Weinstein
    posted to activation dynamics md rhodopsin by xdeupi on 2007-03-26 10:22:13 as **** along with 1 person and 1 group IrinaMoreira LabCompMed
  • Structure and conformational changes in the C-terminal domain of the beta 2-adrenoceptor: Insights from fluorescence resonance energy tranfer studies.
    J Biol Chem (8 March 2007)
    by Sebastien Granier, Samuel Kim, Aaron M M Shafer, Venkata R P R Ratnala, Juan J J Fung, Richard N N Zare, Brian K K Kobilka
    posted to activation b2ar cterm dynamics fret structure by xdeupi on 2007-03-21 11:39:56 as ** along with 1 group LabCompMed
  • Dosage-dependent switch from G protein-coupled to G protein-independent signaling by a GPCR
    The EMBO Journal, Vol. aop, No. current. (14 December 2006)
    by Yutong Sun, Jianyun Huang, Yang Xiang, Murat Bastepe, Harald Juppner, Brian K Kobilka, Jillian J Zhang, Xin-Yun Huang
    posted to activation b2ar drug pharmacology switch by xdeupi on 2007-03-21 11:13:23 as ** along with 1 person and 1 group Guff32 LabCompMed
  • notes Real-time optical recording of beta1-adrenergic receptor activation reveals supersensitivity of the Arg389 variant to carvedilol.
    J Clin Invest, Vol. 117, No. 1. (January 2007), pp. 229-235.
    by F Rochais, JP Vilardaga, VO Nikolaev, M Bünemann, MJ Lohse, S Engelhardt
    posted to activation agonist b2ar helix8 mutation by xdeupi on 2007-03-12 14:39:00 as ***** along with 1 group LabCompMed
  • Common structural requirements for heptahelical domain function in class A and class C GPCRS.
    J Biol Chem (19 February 2007)
    by Virginie Binet, Béatrice Duthey, Jennifer Lecaillon, Claire Vol, Julie Quoyer, Gilles Labesse, Jean-Philippe P Pin, Laurent Prézeau
    posted to activation class_c gaba gpcr switch by xdeupi on 2007-02-26 09:21:25 as ** along with 1 group LabCompMed
  • Predisposition of the dark state of rhodopsin to functional changes in structure
    Proteins: Structure, Function, and Bioinformatics, Vol. 65, No. 4. (2006), pp. 970-983.
    by Basak Isin, AJ Rader, Harpreet K Dhiman, Judith Klein-Seetharaman, Ivet Bahar
    posted to activation dynamics modeling rhodopsin by xdeupi on 2007-02-26 09:19:19 as **** along with 1 person and 1 group aqeel LabCompMed
  • How a small change in retinal leads to G-protein activation: initial events suggested by molecular dynamics calculations.
    Proteins, Vol. 66, No. 3. (15 February 2007), pp. 559-574.
    by PS Crozier, MJ Stevens, TB Woolf
    posted to activation dynamics md modeling rhodopsin switch by xdeupi on 2007-02-26 09:15:15 as **** along with 1 group LabCompMed
  • Visual rhodopsin sees the light: Structure and mechanism of G protein signaling.
    J Biol Chem (8 February 2007)
    by Kevin D D Ridge, Krzysztof Palczewski
    posted to activation crystallography review rhodopsin by xdeupi on 2007-02-20 10:11:15 as ** along with 1 group LabCompMed
  • The first extracellular loop of the Saccharomyces cerevisiae GPCR STE2P undergoes a conformational change upon ligand binding.
    J Biol Chem (9 February 2007)
    by Melinda Hauser, Sarah Kauffman, Byung-Kwon K Lee, Fred Naider, Jeffrey M M Becker
    posted to activation binding gpcr loops by xdeupi on 2007-02-20 10:09:06 as ** along with 1 group LabCompMed
  • A methyl group at C7 of 11-cis-retinal allows chromophore formation but affects rhodopsin activation.
    Vision Res (5 October 2006)
    by Laia Bosch, Arnau Cordomí, Marta Domínguez, Darwin Toledo, Margarita Morillo, Juan J J Pérez, Rosana Alvarez, Angel R R de Lera, Pere Garriga
    posted to activation dynamics md rhodopsin by xdeupi on 2007-02-20 09:56:24 as ** along with 1 person and 1 group arnaucordomi LabCompMed
  • NMR analysis of rhodopsin-transducin interactions.
    Vision Res, Vol. 46, No. 27. (December 2006), pp. 4482-4492.
    by KD Ridge, JP Marino, T Ngo, E Ramon, DM Brabazon, NG Abdulaev
    posted to activation gproteins nmr rhodopsin by xdeupi on 2007-02-20 09:54:49 as ** along with 1 group LabCompMed
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