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G-protein-coupled receptors: past, present and future.

by: SJ Hill
Br J Pharmacol, Vol. 147 Suppl 1 (January 2006)


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The G-protein-coupled receptor (GPCR) family represents the largest and most versatile group of cell surface receptors. Drugs active at these receptors have therapeutic actions across a wide range of human diseases ranging from allergic rhinitis to pain, hypertension and schizophrenia. This review provides a brief historical overview of the properties and signalling characteristics of this important family of receptors.British Journal of Pharmacology (2006) 147, S27-S37. doi:10.1038/sj.bjp.0706455.


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