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xdeupi's library [304 articles]

最近录入 xdeupi's 文献库.
  • Investigation of transmembrane proteins using a computational approach.
    BMC genomics, Vol. 9 Suppl 1 (2008)
    by JY Yang, MQ Yang, AK Dunker, Y Deng, X Huang
    posted to transmembrane theory structure membrane_proteins loops gpcr disorder by xdeupi on 2008-10-20 22:23:57 as **
  • Functional role of the extracellular N-terminal domain of neuropeptide Y subfamily receptors in membrane integration and agonist-stimulated internalization.
    Cellular signalling (22 September 2008)
    by Diana Lindner, Cornelia Walther, Anja Tennemann, Annette G G Beck-Sickinger
    posted to tm1 nterm internalization binding activation by xdeupi on 2008-10-20 22:13:34 as **
  • A Functional Polymorphism under Positive Evolutionary Selection in ADRB2 is Associated with Human Intelligence with Opposite Effects in the Young and the Elderly.
    Behavior genetics (15 October 2008)
    by Zoltán Bochdanovits, Florencia M Gosso, Linda van den Berg, Patrizia Rizzu, Tinca J Polderman, Luba M Pardo, Lorna M Houlihan, Michelle Luciano, John M Starr, Sarah E Harris, Ian J Deary, Eco J de Geus, Dorret I Boomsma, Peter Heutink, Danielle Posthuma
    posted to polymorphism b2ar by xdeupi on 2008-10-20 22:08:33 as **
  • Physiological relevance of GPCR oligomerization and its impact on drug discovery
    Drug Discovery Today (14 October 2008)
    by R Panetta, M Greenwood
    posted to review pharmacology ligands gpcr drug disease dimer by xdeupi on 2008-10-16 09:57:50 as **
  • Activation of the mu opioid receptor involves conformational rearrangements of multiple transmembrane domains.
    Biochemistry, Vol. 47, No. 40. (7 October 2008), pp. 10576-10586.
    by W Xu, A Sanz, L Pardo, LY Liu-Chen
    posted to switch opioid modeling cys_scanning activation by xdeupi on 2008-10-15 10:57:26 as **
  • Accelerated Dephosphorylation of the beta2-Adrenergic Receptor by Mutation of the C-Terminal Lysines: Effects on Ubiquitination, Intracellular Trafficking, and Degradation.
    Biochemistry (9 October 2008)
    by Wei Liang, Quang Hoang, Richard B Clark, Peter H Fishman
    posted to internalization grk activation by xdeupi on 2008-10-15 10:51:58 as **
  • Fluorescent GPCR ligands as new tools in pharmacology.
    Current medicinal chemistry, Vol. 15, No. 21. (2008), pp. 2132-2143.
    by K Kuder, K Kieć-Kononowicz
    posted to ligands imaging fluorescence drug binding agonist activation by xdeupi on 2008-10-15 10:30:17 as **
  • The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist
    Science (2 October 2008), 1164772.
    by Veli-Pekka Jaakola, Mark T Griffith, Michael A Hanson, Vadim Cherezov, Ellen Y Chien, Robert J Lane, Adriaan P Ijzerman, Raymond C Stevens
    posted to xray structure ligands gpcr docking crystallography binding by xdeupi on 2008-10-15 10:02:26 as ** along with 1 person and 1 group cen4ik LabCompMed
  • Structure of a β1-adrenergic G-protein-coupled receptor
    Nature (25 June 2008)
    by Tony Warne, Maria J Serrano-Vega, Jillian G Baker, Rouslan Moukhametzianov, Patricia C Edwards, Richard Henderson, Andrew GW Leslie, Christopher G Tate, Gebhard FX Schertler
    posted to xray structure ligands drug docking binding b2ar by xdeupi on 2008-09-16 10:15:17 as ** along with 2 people and 2 groups merj TonyIvetac LabCompMed McCammon
  • Seven transmembrane receptors: a brief personal retrospective.
    Biochimica et biophysica acta, Vol. 1768, No. 4. (April 2007), pp. 748-755.
    by RJ Lefkowitz
    posted to review lmc_101 gpcr by xdeupi on 2008-09-02 11:50:30 as ** along with 1 person IrinaMoreira
  • Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin.
    Science (New York, N.Y.), Vol. 274, No. 5288. (1 November 1996), pp. 768-770.
    by DL Farrens, C Altenbach, K Yang, WL Hubbell, HG Khorana
    posted to activation rhodopsin tm6 by xdeupi on 2008-08-08 19:00:11 as ** along with 1 group LabCompMed
  • Proline-induced distortions of transmembrane helices.
    J Mol Biol, Vol. 323, No. 5. (8 November 2002), pp. 951-960.
    by FS Cordes, JN Bright, MS Sansom
    posted to activation helix membrane_proteins pro-kink structure theory transmembrane by xdeupi on 2008-05-27 11:58:27 as ** along with 1 person thaliana
  • Analysis of side-chain rotamers in transmembrane proteins.
    Biophysical journal, Vol. 87, No. 5. (November 2004), pp. 3460-3469.
    by AK Chamberlain, JU Bowie
    posted to flexibility hbond helix membrane_proteins ser serthr_paper structure thr transmembrane by xdeupi on 2008-05-15 11:35:47 as ** along with 1 person and 1 group carlk LabCompMed
  • Recruitment of beta-arrestin2 to the dopamine D2 receptor: Insights into anti-psychotic and anti-parkinsonian drug receptor signaling.
    Neuropharmacology (8 April 2008)
    by Ib V V Klewe, Søren M M Nielsen, Louise Tarpø, Eneko Urizar, Concetta Dipace, Jonathan A A Javitch, Ulrik Gether, Jan Egebjerg, Kenneth V V Christensen
    posted to activation active-state agonist arrestin biased_agonism binding disease fluorescence imaging internalization pharmacology by xdeupi on 2008-05-13 16:24:49 as **
  • Crystal structure of squid rhodopsin with intracellularly extended cytoplasmic region.
    The Journal of biological chemistry (6 May 2008)
    by Tatsuro Shimamura, Kenji Hiraki, Naoko Takahashi, Tetsuya Hori, Hideo Ago, Katsuyoshi Masuda, Koji Takio, Masaji Ishiguro, Masashi Miyano
    posted to crystallography cterm gpcr rhodopsin structure xray by xdeupi on 2008-05-13 16:19:24 as ** along with 1 group LabCompMed
  • Crystallizing thinking about the beta2-adrenergic receptor.
    Mol Pharmacol (31 January 2008)
    by Arun K K Shukla, Jin-Peng P Sun, Robert J J Lefkowitz
    posted to b2ar crystallography gpcr review by xdeupi on 2008-05-13 16:09:07 as ** along with 3 people agrossfield tkershaw merj
  • Transmembrane helix uniformity examined by spectral mapping of torsion angles.
    Structure (London, England : 1993), Vol. 16, No. 5. (May 2008), pp. 787-797.
    by RC Page, S Kim, TA Cross
    posted to hbond helix structure transmembrane by xdeupi on 2008-05-13 16:04:28 as **
  • Uniformity, ideality, and hydrogen bonds in transmembrane alpha-helices.
    Biophysical journal, Vol. 83, No. 4. (October 2002), pp. 2084-2095.
    by S Kim, TA Cross
    posted to flexibility hbond helix retinal_binding_proteins structure transmembrane by xdeupi on 2008-05-13 16:00:40 as **
  • Clinical consequences of ADR2 polymorphisms
    Pharmacogenomics, Vol. 9, No. 3. (March 2008), pp. 349-358.
    by Hawkins, A Gregory, Weiss, T Scott, Bleecker, R Eugene
    posted to b2ar disease drug genome pharmacology polymorphism review by xdeupi on 2008-05-03 17:12:39 as **
  • Mechanisms of Inter- and Intramolecular Communication in GPCRs and G Proteins
    J. Am. Chem. Soc. (12 March 2008)
    by F Raimondi, M Seeber, PG Debenedetti, F Fanelli
    posted to activation docking gpcr gproteins by xdeupi on 2008-05-03 17:09:50 as ** along with 1 person paulschlesinger
  • The specificity of binding of glycoprotein hormones to their receptors.
    Cellular and molecular life sciences : CMLS (26 April 2008)
    by G Caltabiano, M Campillo, A De Leener, G Smits, G Vassart, S Costagliola, L Pardo
    posted to activation hormone modeling thyrotropin by xdeupi on 2008-05-03 17:06:33 as ** along with 1 group LabCompMed
  • Functional assays as prismatic views of drug activity: relevance to new drug discovery.
    Journal of receptor and signal transduction research, Vol. 28, No. 1. (2008), pp. 109-125.
    by T Kenakin
    posted to biased_agonism chemokine drug pharmacology review by xdeupi on 2008-05-03 17:03:08 as **
  • Computational analysis of membrane proteins: genomic occurrence, structure prediction and helix interactions.
    Q Rev Biophys, Vol. 37, No. 2. (May 2004), pp. 121-146.
    by U Lehnert, Y Xia, TE Royce, CS Goh, Y Liu, A Senes, H Yu, ZL Zhang, DM Engelman, M Gerstein
    posted to membrane_proteins review serthr_paper structure theory transmembrane by xdeupi on 2008-05-01 19:11:17 as ***** along with 1 person thaliana
  • Stable Interactions Between the Transmembrane Domains of the Adenosine A2A Receptor.
    Protein science : a publication of the Protein Society (23 April 2008)
    by Damien Thevenin, Tzvetana Lazarova
    posted to folding gpcr structure transmembrane by xdeupi on 2008-04-28 11:00:29 as ** along with 1 person IrinaMoreira
  • notes Transmembrane proteins in the Protein Data Bank: identification and classification.
    Bioinformatics, Vol. 20, No. 17. (22 November 2004), pp. 2964-2972.
    by GE Tusnády, Z Dosztányi, I Simon
    posted to structure membrane_proteins lmc_101 helix by xdeupi on 2008-04-08 13:55:52 as ** along with 4 people and 1 group kallberg chrn sebk viktor21614 LabCompMed
  • Retinylidene proteins: structures and functions from archaea to humans.
    Annual review of cell and developmental biology, Vol. 16 (2000), pp. 365-392.
    by JL Spudich, CS Yang, KH Jung, EN Spudich
    posted to retinal retinal_binding_proteins review rhodopsin structure by xdeupi on 2008-04-08 11:33:18 as ** along with 1 group LabCompMed
  • Crystal structure of rhodopsin: implications for vision and beyond.
    Current opinion in structural biology, Vol. 11, No. 4. (August 2001), pp. 420-426.
    by T Okada, K Palczewski
    posted to retinal retinal_binding_proteins review rhodopsin structure by xdeupi on 2008-04-08 11:29:02 as ** along with 1 group LabCompMed
  • notes Protein-Protein Docking with Backbone Flexibility
    Journal of Molecular Biology, Vol. 373, No. 2. (19 October 2007), pp. 503-519.
    by Chu Wang, Philip Bradley, David Baker
    posted to docking flexibility modeling theory by xdeupi on 2008-04-07 14:23:45 as ** along with 4 people and 2 groups csrocha barry jwm Ema structural_bioinformatics Bioinformatics
  • notes Protein-Protein Docking with Simultaneous Optimization of Rigid-body Displacement and Side-chain Conformations
    Journal of Molecular Biology, Vol. 331, No. 1. (1 August 2003), pp. 281-299.
    by Jeffrey J Gray, Stewart Moughon, Chu Wang, Ora Schueler-Furman, Brian Kuhlman, Carol A Rohl, David Baker
    posted to dimer docking modeling theory by xdeupi on 2008-04-07 14:18:56 as ** along with 4 people ima bluvsh1 selrac timg
  • The relation between the divergence of sequence and structure in proteins.
    EMBO J, Vol. 5, No. 4. (April 1986), pp. 823-826.
    by C Chothia, AM Lesk
    posted to sequence structure theory by xdeupi on 2008-04-02 15:48:23 as ** along with 7 people and 6 groups ana pansapiens jwm Einat marcius ffranca insectopalo structural_bioinformatics Radiation_Damage Stressosome Bioinformatics BioinfoCIPF SGU-CIPF
  • FRET Study of Membrane Proteins: Simulation-Based Fitting for Analysis of Membrane Protein Embedment and Association
    Biophys. J., Vol. 91, No. 2. (15 July 2006), pp. 454-466.
    by Petr V Nazarov, Rob B Koehorst, Werner L Vos, Vladimir V Apanasovich, Marcus A Hemminga
    posted to dimer fluorescence fret theory by xdeupi on 2008-04-02 13:50:03 as ***** along with 1 person dimka
  • Chemogenomic approaches to rational drug design
    Br J Pharmacol, Vol. 152, No. 1. (29 May 2007), pp. 38-52.
    by D Rognan
    posted to agonist binding drug ligands pharmacology priviledged_structures by xdeupi on 2008-03-28 15:54:47 as ** along with 4 people and 3 groups jmrivort jerome_ucsf_slb jyuh tjimenez LabCompMed G-quadruplex Supramolecular
  • Efficient coupling of transducin to monomeric rhodopsin in a phospholipid bilayer.
    J Biol Chem (22 November 2007)
    by Matthew R R Whorton, Beata Jastrzebska, Paul S-H S Park, Dimitrios Fotiadis, Andreas Engel, Krzysztof Palczewski, Roger K K Sunahara
    posted to activation dimer gproteins rhodopsin by xdeupi on 2008-03-12 17:12:36 as ** along with 1 person and 1 group gcaltabiano LabCompMed
  • Mapping of contact sites in complex formation between transducin and light-activated rhodopsin by covalent crosslinking: use of a photoactivatable reagent.
    Proc Natl Acad Sci U S A, Vol. 98, No. 9. (24 April 2001), pp. 4877-4882.
    by K Cai, Y Itoh, HG Khorana
    posted to activation active-state gproteins icl3 rhodopsin by xdeupi on 2008-03-12 15:47:55 as ** along with 1 person IrinaMoreira
  • Mapping of contact sites in complex formation between light-activated rhodopsin and transducin by covalent crosslinking: use of a chemically preactivated reagent.
    Proc Natl Acad Sci U S A, Vol. 98, No. 9. (24 April 2001), pp. 4883-4887.
    by Y Itoh, K Cai, HG Khorana
    posted to active-state gproteins icl3 rhodopsin by xdeupi on 2008-03-12 15:46:28 as ** along with 1 person IrinaMoreira
  • Heterotrimeric G protein activation by G-protein-coupled receptors.
    Nat Rev Mol Cell Biol (28 November 2007)
    by William M M Oldham, Heidi E E Hamm
    posted to activation erc_grant gproteins rhodopsin by xdeupi on 2008-03-11 14:30:28 as ** along with 4 people and 2 groups dchughes Fritz mingzhi laurabailey neurolit LabCompMed
  • notes Chloroethylclonidine and 2-aminoethyl methanethiosulfonate recognize two different conformations of the human alpha(2A)-adrenergic receptor.
    J Biol Chem, Vol. 274, No. 31. (30 July 1999), pp. 21867-21872.
    by A Marjamäki, H Frang, M Pihlavisto, AM Hoffrén, T Salminen, MS Johnson, J Kallio, JA Javitch, M Scheinin
    posted to activation binding cys_scanning drug ligands tm5 by xdeupi on 2008-03-07 15:14:37 as ** along with 1 group LabCompMed
  • Identification of the Binding Sites of the SR49059 Nonpeptide Antagonist into the V1a Vasopressin Receptor Using Sulfydryl-reactive Ligands and Cysteine Mutants as Chemical Sensors
    J. Biol. Chem., Vol. 278, No. 41. (10 October 2003), pp. 40010-40019.
    by Chouaib Tahtaoui, Marie-Noelle Balestre, Philippe Klotz, Didier Rognan, Claude Barberis, Bernard Mouillac, Marcel Hibert
    posted to binding cys_scanning peptide vasopressin by xdeupi on 2008-02-28 16:16:02 as **
  • Transducin activation by nanoscale lipid bilayers containing one and two rhodopsins.
    J Biol Chem, Vol. 282, No. 20. (18 May 2007), pp. 14875-14881.
    by TH Bayburt, AJ Leitz, G Xie, DD Oprian, SG Sligar
    posted to activation dimer lipids rhodopsin by xdeupi on 2008-02-27 11:06:04 as ***
  • beta-Arrestin-biased Agonism at the beta2-Adrenergic Receptor.
    J Biol Chem, Vol. 283, No. 9. (29 February 2008), pp. 5669-5676.
    by MT Drake, JD Violin, EJ Whalen, JW Wisler, SK Shenoy, RJ Lefkowitz
    posted to activation agonist arrestin b2ar biased_agonism drug gproteins imaging internalization ligands pharmacology by xdeupi on 2008-02-27 10:39:07 as *** along with 1 group LabCompMed
  • Chemistry. Following the flow of energy in biomolecules.
    Science, Vol. 310, No. 5750. (11 November 2005), pp. 980-982.
    by PM Champion
    posted to activation retinal review rhodopsin by xdeupi on 2007-07-30 17:02:29 as **** along with 1 group LabCompMed
  • Proton movement and photointermediate kinetics in rhodopsin mutants.
    Biochemistry, Vol. 45, No. 17. (2 May 2006), pp. 5430-5439.
    by JW Lewis, I Szundi, MA Kazmi, TP Sakmar, DS Kliger
    posted to activation protonation rhodopsin by xdeupi on 2007-07-30 17:00:28 as ** along with 1 group LabCompMed
  • Primary photoprocess in vision: minimal motion to reach the photo- and bathorhodopsin intermediates.
    J Phys Chem B, Vol. 109, No. 18. (12 May 2005), pp. 9104-9110.
    by F Blomgren, S Larsson
    posted to activation retinal rhodopsin theory by xdeupi on 2007-07-30 16:59:24 as ** along with 1 group LabCompMed
  • Photoisomerization mechanism of rhodopsin and 9-cis-rhodopsin revealed by x-ray crystallography.
    Biophys J, Vol. 92, No. 12. (15 June 2007)
    by H Nakamichi, V Buss, T Okada
    posted to activation retinal rhodopsin by xdeupi on 2007-07-30 16:57:47 as ** along with 1 group LabCompMed
  • Coupling of retinal isomerization to the activation of rhodopsin
    PNAS, Vol. 101, No. 27. (6 July 2004), pp. 10048-10053.
    by Ashish B Patel, Evan Crocker, Markus Eilers, Amiram Hirshfeld, Mordechai Sheves, Steven O Smith
    posted to activation active-state nmr retinal rhodopsin by xdeupi on 2007-07-30 15:16:18 as ** along with 1 group LabCompMed
  • The G protein-coupled receptor kinase (GRK) interactome: role of GRKs in GPCR regulation and signaling.
    Biochim Biophys Acta, Vol. 1768, No. 4. (April 2007), pp. 913-922.
    by C Ribas, P Penela, C Murga, A Salcedo, C García-Hoz, M Jurado-Pueyo, I Aymerich, F Mayor
    posted to activation arrestin gpcr grk by xdeupi on 2007-07-30 14:59:43 as ** along with 1 group LabCompMed
  • A concept for G protein activation by G protein-coupled receptor dimers: the transducin/rhodopsin interface.
    Photochem Photobiol Sci, Vol. 3, No. 6. (June 2004), pp. 628-638.
    by S Filipek, KA Krzysko, D Fotiadis, Y Liang, DA Saperstein, A Engel, K Palczewski
    posted to active-state gproteins modeling rhodopsin structure by xdeupi on 2007-07-11 16:54:09 as ** along with 1 person and 1 group cen4ik LabCompMed
  • Refinement of a homology model of the mu-opioid receptor using distance constraints from intrinsic and engineered zinc-binding sites.
    Biochemistry, Vol. 43, No. 27. (13 July 2004), pp. 8700-8710.
    by CB Fowler, ID Pogozheva, H LeVine, HI Mosberg
    posted to active-state modeling opioid structure theory by xdeupi on 2007-07-11 16:51:53 as ** along with 1 person and 1 group merj LabCompMed
  • Complex of an active mu-opioid receptor with a cyclic peptide agonist modeled from experimental constraints.
    Biochemistry, Vol. 43, No. 50. (21 December 2004), pp. 15796-15810.
    by CB Fowler, ID Pogozheva, AL Lomize, H LeVine, HI Mosberg
    posted to active-state gproteins modeling opioid structure by xdeupi on 2007-07-11 16:50:15 as ** along with 1 group LabCompMed
  • Modeling of the complex between transducin and photoactivated rhodopsin, a prototypical G-protein-coupled receptor.
    Biochemistry, Vol. 46, No. 16. (24 April 2007), pp. 4734-4744.
    by GV Nikiforovich, CM Taylor, GR Marshall
    posted to gproteins modeling rhodopsin by xdeupi on 2007-07-11 11:05:58 as ** along with 1 group LabCompMed
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