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Shaping space: The possible and the attainable in RNA genotype-phenotype mapping

by: W Fontana, P Schuster
J. Theor. Biol. (1998)


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Understanding which phenotypes are accessible from which genotypes is fundamental for understanding the evolutionary process. This notion of accessibility can be used to define a relation of nearness among phenotypes, independently of their similarity. Because of neutrality, phenotypes denote equivalence classes of genotypes. The definition of neighborhood relations among phenotypes relies, therefore, on the statistics of neighborhood relations among equivalence classes of genotypes in genotype ...


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