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Microrheology as a tool for high-throughput screening

by: V Breedveld, DJ Pine
Journal of Materials Science, Vol. 38, No. 22. (1 November 2003), pp. 4461-4470.

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Microrheology can be used for high-throughput screening of the rheological properties of sample libraries of complex fluids. Two passive techniques are particularly suitable: video microscopy and diffusing-wave spectroscopy. The techniques complement each other very well and can be applied to samples that offer different experimental challenges. We offer a thorough analysis of the strengths and limitations of microrheology with the emphasis on high-throughput applications. To illustrate the potential of microrheology, results are presented for two representative cases: the rheological screening of aqueous solutions of a block copolypeptide library and the rheological phase diagram of a water/surfactant/salt system.


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