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wbrady5's phase_i [34 articles]

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  • An optimization algorithm for designing phase I cancer clinical trials
    Contemporary Clinical Trials, Vol. 29, No. 2. (March 2008), pp. 102-108.
    by Hui Jiang, Yifan Liu, Zheng Su
    posted to algorithm_based_design clinical_trial phase_i by wbrady5 on 2008-03-05 16:30:06 as **
  • A Bayesian evaluation of enrolling additional patients at the maximum tolerated dose in Phase I trials
    Contemporary Clinical Trials, Vol. 26, No. 2. (April 2005), pp. 131-140.
    by Mithat Gonen
    posted to bayesian phase_i by wbrady5 on 2008-02-26 02:28:35 as **
  • Clinical Trial Designs for Cytostatic Agents: Are New Approaches Needed?
    J Clin Oncol, Vol. 19, No. 1. (1 January 2001), pp. 265-272.
    by Edward L Korn, Susan G Arbuck, James M Pluda, Richard Simon, Richard S Kaplan, Michaele C Christian
    posted to clinical_trial cytostatic phase_i phase_ii phase_iii by wbrady5 on 2008-02-22 15:01:50 as **
  • Optimal phase I dose-escalation trial designs in oncology - A simulation study
    Statistics in Medicine, Vol. 9999, No. 9999. (2007), n/a.
    by Oke Gerke, Harald Siedentop
    posted to clinical_trial phase_i simulation by wbrady5 on 2008-01-26 00:22:32 as **
  • Design and Analysis of Phase I Clinical Trials
    Biometrics, Vol. 45, No. 3. (1989), pp. 925-937.
    by Barry E Storer
    posted to clinical_trial phase_i by wbrady5 on 2008-01-17 22:28:02 as read
  • 3 + 3 != (Rolling) 6
    J Clin Oncol, Vol. 26, No. 2. (10 January 2008), pp. 170-171.
    by Christine Hartford, Samuel L Volchenboum, Susan L Cohn
    posted to clinical_trial editorial pediatric phase_i by wbrady5 on 2008-01-09 22:30:31 as **
  • Shortening the Timeline of Pediatric Phase I Trials: The Rolling Six Design
    J Clin Oncol, Vol. 26, No. 2. (10 January 2008), pp. 190-195.
    by Jeffrey M Skolnik, Jeffrey S Barrett, Bhuvana Jayaraman, Dimple Patel, Peter C Adamson
    posted to ab_design clinical_trial pediatric phase_i by wbrady5 on 2008-01-09 22:29:45 as **
  • Statistical properties of the traditional algorithm-based designs for phase I cancer clinical trials
    Biostat, Vol. 2, No. 2. (1 June 2001), pp. 203-215.
    by Yong Lin, Weichung J Shih
    posted to algorithm_based_design clinical_trial phase_i by wbrady5 on 2008-01-09 15:11:16 as read
  • An investigation of the traditional algorithm-based designs for phase 1 cancer clinical trials
    Drug Information Journal, Vol. 36 (2002), pp. 865-873.
    by S Kang, CW Ahn
    posted to ab_design algorithm_based_design clinical_trial phase_i by wbrady5 on 2008-01-09 15:08:25 as read
  • Phase I and Phase I/II Dose Finding Algorithms Using Continual Reassessment Method
    (2005), pp. 31-58.
    by John O'Quigley
    edited by John Crowley, Donna P Ankerst
    posted to clinical_trial continual_reassessment_method phase_i phase_ii by wbrady5 on 2008-01-08 16:54:15 as **
  • Accelerated titration designs for phase I clinical trials in oncology
    J. Natl. Cancer Inst., Vol. 89, No. 15. (6 August 1997), pp. 1138-1147.
    by R Simon, B Freidlin, L Rubinstein, SG Arbuck, J Collins, MC Christian
    posted to ab_design clinical_trial phase_i by wbrady5 on 2008-01-07 19:46:36 as read
  • Simulation as a design tool for phase I/II clinical trials: An example from bone marrow transplantation
    Controlled Clinical Trials, Vol. 15, No. 6. (December 1994), pp. 450-462.
    by Ted A Gooley, Paul J Martin, Lloyd D Fisher, Mary Pettinger
    posted to clinical_trial phase_i phase_ii simulation by wbrady5 on 2008-01-07 13:58:52 as **
  • A New Dose-Finding Design for Bivariate Outcomes
    Biometrics, Vol. 59, No. 4. (2003), pp. 1001-1007.
    by Anastasia Ivanova
    posted to bivariate clinical_trial phase_i by wbrady5 on 2008-01-04 22:08:03 as **
  • Two-Dimensional Dose Finding in Discrete Dose Space
    Biometrics, Vol. 61, No. 1. (March 2005), pp. 217-222.
    by Kai Wang, Anastasia Ivanova
    posted to bayesian combination_therapy continual_reassessment_method phase_i by wbrady5 on 2008-01-04 22:05:21 as **
  • Retrospective Analysis of Sequential Dose-Finding Designs
    Biometrics, Vol. 61, No. 3. (2005), pp. 749-756.
    by John O'Quigley
    posted to ab_design clinical_trial continual_reassessment_method phase_i by wbrady5 on 2008-01-04 22:01:02 as **
  • A Parallel Phase III Clinical Trial Design for Combination Therapies
    Biometrics, Vol. 63, No. 2. (June 2007), pp. 429-436.
    by Huang, Xuelin, Biswas, Swati, Oki, Yasuhiro, Issa, Jean-Pierre, Berry, A Donald
    posted to bayesian bivariate clinical_trial combination_therapy phase_i phase_ii toxicity by wbrady5 on 2008-01-04 21:59:15 as **
  • Bayesian Dose-Finding in Phase III Clinical Trials Using Toxicity and Efficacy Odds Ratios
    Biometrics, Vol. 62, No. 3. (September 2006), pp. 777-787.
    by Yin, Guosheng, Li, Yisheng, Ji, Yuan
    posted to adaptive bayesian bivariate clinical_trial phase_i by wbrady5 on 2008-01-04 21:51:07 as **
  • A Bayesian Approach to Jointly Modeling Toxicity and Biomarker Expression in a Phase I/II Dose-Finding Trial
    Biometrics, Vol. 61, No. 2. (June 2005), pp. 343-354.
    by B Nebiyou, Yu Shen
    posted to bayesian biomarker clinical_trial phase_i phase_ii toxicity by wbrady5 on 2008-01-04 21:46:56 as **
  • Sequential Designs for Phase I Clinical Trials with Late-Onset Toxicities
    Biometrics, Vol. 56, No. 4. (2000), pp. 1177-1182.
    by Ying K Cheung, Rick Chappell
    posted to clinical_trial continual_reassessment_method phase_i by wbrady5 on 2008-01-04 21:45:12 as read
  • Designs for Single- or Multiple-Agent Phase I Trials
    Biometrics, Vol. 60, No. 3. (2004), pp. 661-669.
    by Mark R Conaway, Stephanie Dunbar, Shyamal D Peddada
    posted to clinical_trial combination_therapy phase_i toxicity by wbrady5 on 2008-01-04 21:35:23 as **
  • Bayesian Optimal Designs for Phase I Clinical Trials
    Biometrics, Vol. 59, No. 3. (2003), pp. 591-600.
    by Linda M Haines, Inna Perevozskaya, William F Rosenberger
    posted to bayesian clinical_trial optimal_design phase_i by wbrady5 on 2008-01-04 21:33:54 as **
  • Dose-Finding with Two Agents in Phase I Oncology Trials
    Biometrics, Vol. 59, No. 3. (2003), pp. 487-496.
    by Peter F Thall, Randall E Millikan, Peter Mueller, Sang J Lee
    posted to bayesian clinical_trial combination_therapy phase_i toxicity by wbrady5 on 2008-01-04 21:31:11 as read
  • Adaptive Dose Selection Using Efficacy-Toxicity Trade-Offs: Illustrations and Practical Considerations
    Journal of Biopharmaceutical Statistics, Vol. 16, No. 5. (2006), pp. 623-638.
    by Peter F Thall, John D Cook, Elihu H Estey
    posted to bayesian bivariate clinical_trial continual_reassessment_method phase_i by wbrady5 on 2008-01-02 22:12:27 as **
  • An Evaluation of a Bayesian Method of Dose Escalation Based on Bivariate Binary Responses
    Journal of Biopharmaceutical Statistics, Vol. 14, No. 4. (2004), pp. 969-983.
    by John Whitehead, Yinghui Zhou, John Stevens, Graham Blakey
    posted to bayesian bivariate continual_reassessment_method phase_i by wbrady5 on 2008-01-02 22:09:55 as **
  • Three-dose-cohort designs in cancer phase I trials
    Statistics in Medicine, Vol. 9999, No. 9999. (2007), n/a.
    by Bo Huang, Rick Chappell
    posted to continual_reassessment_method multiple_dosing phase_i by wbrady5 on 2007-12-21 21:50:21 as **
  • Phase I Studies of Chemotherapeutic Agents in Cancer Patients: A Review of the Designs
    Journal of Biopharmaceutical Statistics, Vol. 16, No. 5. (2006), pp. 579-604.
    by Douglas M Potter
    posted to clinical_trial phase_i review by wbrady5 on 2007-12-21 19:46:24 as read
  • Another look at two phase I clinical trial designs
    Statistics in Medicine, Vol. 18, No. 20. (1999), pp. 2683-2690.
    by John O'Quigley
    posted to continual_reassessment_method phase_i up_and_down_design by wbrady5 on 2007-12-11 19:57:08 as read
  • Methods for dose finding studies in cancer clinical trials: A review and results of a monte carlo study
    Statistics in Medicine, Vol. 10, No. 11. (1991), pp. 1647-1664.
    by John O'Quigley, Sylvie Chevret
    posted to phase_i by wbrady5 on 2007-12-11 19:56:25 as **
  • AN EXTENSION OF THE CONTINUAL REASSESSMENT METHODS USING A PRELIMINARY UP-AND-DOWN DESIGN IN A DOSE FINDING STUDY IN CANCER PATIENTS, IN ORDER TO INVESTIGATE A GREATER RANGE OF DOSES
    Statistics in Medicine, Vol. 14, No. 9. (1995), pp. 911-922.
    by Susanne Møller
    posted to continual_reassessment_method phase_i up_and_down_design by wbrady5 on 2007-12-11 19:53:56 as read
  • Some practical improvements in the continual reassessment method for phase I studies
    Statistics in Medicine, Vol. 14, No. 11. (1995), pp. 1149-1161.
    by Steven N Goodman, Marianna L Zahurak, Steven Piantadosi
    posted to continual_reassessment_method phase_i by wbrady5 on 2007-12-11 19:46:53 as read
  • Escalation, group and <I>A</I> + <I>B</I> designs for dose-finding trials
    Statistics in Medicine, Vol. 25, No. 21. (2006), pp. 3668-3678.
    by Anastasia Ivanova
    posted to ab_design phase_i by wbrady5 on 2007-12-11 19:31:52 as read
  • A non-parametric approach to the design and analysis of two-dimensional dose-finding trials
    Statistics in Medicine, Vol. 23, No. 12. (2004), pp. 1861-1870.
    by Anastasia Ivanova, Kai Wang
    posted to bivariate combination_therapy nonparametric phase_i toxicity by wbrady5 on 2007-12-11 18:50:11 as read
  • An adaptive phase I design for identifying a biologically optimal dose for dual agent drug combinations
    Statistics in Medicine, Vol. 26, No. 11. (2007), pp. 2317-2330.
    by Sumithra J Mandrekar, Yue Cui, Daniel J Sargent
    posted to bivariate combination_therapy continuation-ratio_model efficacy phase_i toxicity by wbrady5 on 2007-12-11 18:48:20 as read
  • Optimal designs and limiting optimal designs for a trinomial response
    Journal of Statistical Planning and Inference, Vol. 126, No. 1. (1 November 2004), pp. 347-360.
    by Kelly, Kathryn Chaloner
    posted to bivariate continuation-ratio_model optimal_design phase_i phase_ii trinomial_responses by wbrady5 on 2007-10-29 20:25:42 as **
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