Effects of dietary retinoids and carotenoids on immune development

@article{citeulike:2478080, abstract = {Carotenoids and retinoids are groups of nutritionally-relevant compounds present in many foods of plant origin (carotenoids) and animal origin (mainly retinoids). Their levels in human subjects vary depending on the diversity and amount of the individual's nutrient intake. Some carotenoids and retinoids have been investigated for their effects on the immune system both <em>in vitro</em> and <em>in vivo</em>. It has been shown that retinoids have the potential to mediate or induce proliferative and differentiating effects on several immune-competent cells, and various carotenoids are known to be inducers of immune function. The immune-modulating effects of retinoids have been well documented, while the effects of carotenoids on the immune system have not been investigated as extensively, because little is known about their molecular mechanism of action. The present review will mainly focus on the molecular mechanism of action of retinoids and particularly carotenoids, their nutritional origin and intake, their transfer from the maternal diet to the child and their effects or potential effects on the developing immune system.}, author = {R?hl, Ralph }, citeulike-article-id = {2478080}, doi = {http://dx.doi.org/10.1017/S002966510600509X}, journal = {Proceedings of the Nutrition Society}, keywords = {carotenoid, diet, immune, retinoid}, number = {03}, pages = {458--469}, posted-at = {2008-03-06 09:54:33}, priority = {4}, title = {Effects of dietary retinoids and carotenoids on immune development}, url = {http://dx.doi.org/10.1017/S002966510600509X}, volume = {66}, year = {2007} }

TY - JOUR ID - citeulike:2478080 L3 - citeulike-article-id:2478080 N2 - Carotenoids and retinoids are groups of nutritionally-relevant compounds present in many foods of plant origin (carotenoids) and animal origin (mainly retinoids). Their levels in human subjects vary depending on the diversity and amount of the individual's nutrient intake. Some carotenoids and retinoids have been investigated for their effects on the immune system both <em>in vitro</em> and <em>in vivo</em>. It has been shown that retinoids have the potential to mediate or induce proliferative and differentiating effects on several immune-competent cells, and various carotenoids are known to be inducers of immune function. The immune-modulating effects of retinoids have been well documented, while the effects of carotenoids on the immune system have not been investigated as extensively, because little is known about their molecular mechanism of action. The present review will mainly focus on the molecular mechanism of action of retinoids and particularly carotenoids, their nutritional origin and intake, their transfer from the maternal diet to the child and their effects or potential effects on the developing immune system. IS - 03 JF - Proceedings of the Nutrition Society EP - 469 TI - Effects of dietary retinoids and carotenoids on immune development VL - 66 SP - 458 KW - carotenoid KW - diet KW - immune KW - retinoid AU - R?hl, Ralph PY - 2007//16/ UR - http://dx.doi.org/10.1017/S002966510600509X ER -