Blast2GO: A Comprehensive Suite for Functional Analysis in Plant Genomics

@article{IJPG_Conesa_Goetz, abstract = {Functional annotation of novel sequence data is a primary requirement for the utilization of functional genomics approaches in plant research. In this paper, we describe the Blast2GO suite as a comprehensive bioinformatics tool for functional annotation of sequences and data mining on the resulting annotations, primarily based on the gene ontology (GO) vocabulary. Blast2GO optimizes function transfer from homologous sequences through an elaborate algorithm that considers similarity, the extension of the homology, the database of choice, the GO hierarchy, and the quality of the original annotations. The tool includes numerous functions for the visualization, management, and statistical analysis of annotation results, including gene set enrichment analysis. The application supports InterPro, enzyme codes, KEGG pathways, GO direct acyclic graphs (DAGs), and GOSlim. Blast2GO is a suitable tool for plant genomics research because of its versatility, easy installation, and friendly use.}, author = {Conesa, Ana and G\"{o}tz, Stefan }, citeulike-article-id = {2797878}, journal = {International Journal of Plant Genomics}, keywords = {annotation, b2g, blast2go, my\_papers}, number = {2008}, pages = {1--12}, posted-at = {2008-05-14 13:13:38}, priority = {2}, title = {Blast2GO: A Comprehensive Suite for Functional Analysis in Plant Genomics}, volume = {2008}, year = {2008} }

TY - JOUR ID - IJPG_Conesa_Goetz L3 - citeulike-article-id:2797878 TI - Blast2GO: A Comprehensive Suite for Functional Analysis in Plant Genomics JF - International Journal of Plant Genomics VL - 2008 IS - 2008 SP - 1 EP - 12 N2 - Functional annotation of novel sequence data is a primary requirement for the utilization of functional genomics approaches in plant research. In this paper, we describe the Blast2GO suite as a comprehensive bioinformatics tool for functional annotation of sequences and data mining on the resulting annotations, primarily based on the gene ontology (GO) vocabulary. Blast2GO optimizes function transfer from homologous sequences through an elaborate algorithm that considers similarity, the extension of the homology, the database of choice, the GO hierarchy, and the quality of the original annotations. The tool includes numerous functions for the visualization, management, and statistical analysis of annotation results, including gene set enrichment analysis. The application supports InterPro, enzyme codes, KEGG pathways, GO direct acyclic graphs (DAGs), and GOSlim. Blast2GO is a suitable tool for plant genomics research because of its versatility, easy installation, and friendly use. KW - annotation KW - b2g KW - blast2go KW - my_papers AU - Conesa, Ana AU - Götz, Stefan PY - 2008/// ER -