Primer on the human genome.

@article{citeulike:1447965, abstract = {The study of the expression patterns of many genes, or even the entire genome, is now routinely possible. Such powerful tools have enabled hypothesis-generating research at a scale never before possible. Moreover, spatially or temporally linked gene and protein expression, implying co-regulation and functional relatedness, has led to the identification of particular clusters of genes important for fundamental biologic processes, such as development and cancer. Not only is this expected to yield further mechanistic insights into disease processes, but perhaps most exciting, it will likely establish the foundation of predictive medicine, in which understanding of individual genomic signatures leads to the use of appropriately targeted therapy. LEARNING OBJECTIVE: At the conclusion of this learning activity, participants should be able to understand the fundamental tenets of molecular biology as they relate to the field of genomics.}, address = {Department of Dermatology, Harvard Medical School, USA.}, author = {Tsai, K. Y. and Tsao, H. }, citeulike-article-id = {1447965}, doi = {10.1016/j.jaad.2006.10.985}, issn = {1097-6787}, journal = {J Am Acad Dermatol}, month = {May}, number = {5}, pages = {719--735}, posted-at = {2007-07-11 09:47:57}, priority = {2}, title = {Primer on the human genome.}, url = {http://dx.doi.org/10.1016/j.jaad.2006.10.985}, volume = {56}, year = {2007} }

TY - JOUR ID - citeulike:1447965 L3 - citeulike-article-id:1447965 TI - Primer on the human genome. JF - J Am Acad Dermatol VL - 56 IS - 5 SP - 719 EP - 735 AD - Department of Dermatology, Harvard Medical School, USA. SN - 1097-6787 N2 - The study of the expression patterns of many genes, or even the entire genome, is now routinely possible. Such powerful tools have enabled hypothesis-generating research at a scale never before possible. Moreover, spatially or temporally linked gene and protein expression, implying co-regulation and functional relatedness, has led to the identification of particular clusters of genes important for fundamental biologic processes, such as development and cancer. Not only is this expected to yield further mechanistic insights into disease processes, but perhaps most exciting, it will likely establish the foundation of predictive medicine, in which understanding of individual genomic signatures leads to the use of appropriately targeted therapy. LEARNING OBJECTIVE: At the conclusion of this learning activity, participants should be able to understand the fundamental tenets of molecular biology as they relate to the field of genomics. AU - Tsai, KY AU - Tsao, H PY - 2007/05// UR - http://dx.doi.org/10.1016/j.jaad.2006.10.985 ER -