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giovanni's library [858 articles]

最近录入 giovanni's 文献库:按阅读优先等级排序.
  • Transcriptional Repression of PGC-1alpha by Mutant Huntingtin Leads to Mitochondrial Dysfunction and Neurodegeneration.
    Cell, Vol. 127, No. 1. (6 October 2006), pp. 59-69.
    by L Cui, H Jeong, F Borovecki, CN Parkhurst, N Tanese, D Krainc
  • Mining gene expression profiles: expression signatures as cancer phenotypes
    Nature Reviews Genetics, Vol. 8, No. 8. (03 July 2007), pp. 601-609.
    by Joseph R Nevins, Anil Potti
  • Nuclear receptors as targets for drug development: molecular mechanisms for regulation of obesity and insulin resistance by peroxisome proliferator-activated receptor gamma, CREB-binding protein, and adiponectin.
    J Pharmacol Sci, Vol. 97, No. 2. (February 2005), pp. 164-170.
    posted to diabetes pgc1-alpha by giovanni on 2007-03-08 15:00:50 as **** along with 1 group GeschwindLab
  • Linking publication, gene and protein data
    Nat Cell Biol, Vol. 8, No. 11. (November 2006), pp. 1183-1189.
    by Paul Kersey, Rolf Apweiler
  • Common kibra alleles are associated with human memory performance.
    Science, Vol. 314, No. 5798. (20 October 2006), pp. 475-478.
  • Bayesian mapping of genotype × expression interactions in quantitative and qualitative traits
    Heredity, Vol. aop, No. current.
    by F Hoti, MJ Sillanpää,
  • A gene-centric approach to genome-wide association studies
    Nature Reviews Genetics, Vol. 7, No. 11., pp. 885-891.
    by Eric Jorgenson, John S Witte
  • Genetics of global gene expression
    Nature Reviews Genetics, Vol. 7, No. 11., pp. 862-872.
    by Matthew V Rockman, Leonid Kruglyak
  • Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
    Science, Vol. 314, No. 5796. (6 October 2006), pp. 130-133.
    by M Neumann, DM Sampathu, LK Kwong, AC Truax, MC Micsenyi, TT Chou, J Bruce, T Schuck, M Grossman, CM Clark, LF McCluskey, BL Miller, E Masliah, IR Mackenzie, H Feldman, W Feiden, HA Kretzschmar, JQ Trojanowski, VM Lee
    posted to tau by giovanni on 2006-10-13 18:54:18 as **** along with 1 person and 1 group inbetweener GeschwindLab
  • Evaluation of DNA microarray results with quantitative gene expression platforms
    Nature Biotechnology, Vol. 24, No. 9. (08 September 2006), pp. 1115-1122.
    by Roger D Canales, Yuling Luo, James C Willey, Bradley Austermiller, Catalin C Barbacioru, Cecilie Boysen, Kathryn Hunkapiller, Roderick V Jensen, Charles R Knight, Kathleen Y Lee, Yunqing Ma, Botoul Maqsodi, Adam Papallo, Elizabeth H Peters, Karen Poulter, Patricia L Ruppel, Raymond R Samaha, Leming Shi, Wen Yang, Lu Zhang, Federico M Goodsaid
  • The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates
    Nature (10 September 2006)
    by Ivan Ahel, Ulrich Rass, Sherif F El-Khamisy, Sachin Katyal, Paula M Clements, Peter J Mckinnon, Keith W Caldecott, Stephen C West
  • Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration
    Nature (13 August 2006)
    by Jeong W Lee, Kirk Beebe, Leslie A Nangle, Jaeseon Jang, Chantal M Longo-Guess, Susan A Cook, Muriel T Davisson, John P Sundberg, Paul Schimmel, Susan L Ackerman
    posted to neurodegeneration by giovanni on 2006-10-11 18:33:50 as **** along with 1 group GeschwindLab
  • NR4A orphan nuclear receptors are transcriptional regulators of hepatic glucose metabolism
    Nature Medicine, Vol. 12, No. 9. (13 August 2006), pp. 1048-1055.
    by Liming Pei, Hironori Waki, Bhavapriya Vaitheesvaran, Damien C Wilpitz, Irwin J Kurland, Peter Tontonoz
    posted to diabetes nurr1 nurr77 by giovanni on 2006-10-07 18:53:42 as **** along with 1 group GeschwindLab
  • Application of Genome-Wide Single Nucleotide Polymorphism Typing: Simple Association and Beyond
    PLoS Genetics, Vol. 2, No. 10. (1 October 2006), e150.
    by Raphael J Gibbs, Andrew Singleton
  • Genome-wide linkage analysis of 723 affected relative pairs with late-onset Alzheimer's Disease
    Hum. Mol. Genet. (27 August 2007), ddm224.
    by Marian L Hamshere, Peter A Holmans, Dimitrios Avramopoulos, Susan S Bassett, Deborah Blacker, Lars Bertram, Howard Wiener, Nan Rochberg, Rudolph E Tanzi, Amanda Myers, Wavrant-De, Rodney Go, Daniele Fallin, Simon Lovestone, John Hardy, Alison Goate, Michael O'Donovan, Julie Williams, Michael J Owen
    posted to alzheimer association by giovanni on 2007-08-28 16:18:12 as *** along with 1 group GeschwindLab
  • The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome
    PNAS (18 July 2007), 0705408104.
    by Kitt F Petersen, Sylvie Dufour, David B Savage, Stefan Bilz, Gina Solomon, Shin Yonemitsu, Gary W Cline, Douglas Befroy, Laura Zemany, Barbara B Kahn, Xenophon Papademetris, Douglas L Rothman, Gerald I Shulman
    posted to diabetes insulin_r by giovanni on 2007-07-19 17:49:19 as *** along with 1 group GeschwindLab
  • Frataxin is essential for extramitochondrial Fe-S cluster proteins in mammalian tissues
    Hum. Mol. Genet. (27 June 2007), ddm163.
    by Alain Martelli, Marie Wattenhofer-Donze, Stephane Schmucker, Samuel Bouvet, Laurence Reutenauer, Helene Puccio
    posted to frataxin by giovanni on 2007-06-27 22:40:52 as *** along with 1 group GeschwindLab
  • The complementary deoxyribonucleic acid sequence, tissue distribution, and cellular localization of the rat granulin precursor.
    Endocrinology, Vol. 133, No. 6. (December 1993), pp. 2682-2689.
    posted to progranulin by giovanni on 2007-06-27 18:06:50 as *** along with 1 group GeschwindLab
  • Charcot-Marie-Tooth disease-associated mutant tRNA synthetases linked to altered dimer interface and neurite distribution defect
    PNAS (26 June 2007), 0705055104.
    by Leslie A Nangle, Wei Zhang, Wei Xie, Xiang-Lei Yang, Paul Schimmel
    posted to synthethases trna by giovanni on 2007-06-27 16:18:53 as *** along with 1 group GeschwindLab
  • A fundamental system of cellular energy homeostasis regulated by PGC-1alpha.
    Proc Natl Acad Sci U S A, Vol. 104, No. 19. (8 May 2007), pp. 7933-7938.
    posted to pgc1-alpha by giovanni on 2007-06-06 03:00:50 as *** along with 1 person and 1 group jyuh GeschwindLab
  • Association Studies: A genome-wide association approach to mapping the genetic determinants of the transcriptome in human populations
    European Journal of Human Genetics, Vol. aop, No. current.
    by Eric E Schadt,
    posted to association by giovanni on 2006-11-28 17:46:37 as *** along with 1 person and 1 group ccots GeschwindLab
  • Thematic review series: Systems Biology Approaches to Metabolic and Cardiovascular Disorders. Reverse engineering gene networks to identify key drivers of complex disease phenotypes
    J. Lipid Res., Vol. 47, No. 12. (1 December 2006), pp. 2601-2613.
    by Eric E Schadt, Pek Y Lum
  • Mapping complex disease loci in whole-genome association studies
    Nature, Vol. 429, No. 6990. (27 May 2004), pp. 446-452.
    by Christopher S Carlson, Michael A Eberle, Leonid Kruglyak, Deborah A Nickerson
    posted to snp by giovanni on 2006-11-28 15:24:24 as *** along with 1 group GeschwindLab
  • Global variation in copy number in the human genome
    Nature, Vol. 444, No. 7118. (23 November 2006), pp. 444-454.
    by Richard Redon, Shumpei Ishikawa, Karen R Fitch, Lars Feuk, George H Perry, Daniel T Andrews, Heike Fiegler, Michael H Shapero, Andrew R Carson, Wenwei Chen, Eun K Cho, Stephanie Dallaire, Jennifer L Freeman, Juan R Gonzalez, Monica Gratacos, Jing Huang, Dimitrios Kalaitzopoulos, Daisuke Komura, Jeffrey R Macdonald, Christian R Marshall, Rui Mei, Lyndal Montgomery, Kunihiro Nishimura, Kohji Okamura, Fan Shen, Martin J Somerville, Joelle Tchinda, Armand Valsesia, Cara Woodwark, Fengtang Yang, Junjun Zhang, Tatiana Zerjal, Jane Zhang, Lluis Armengol, Donald F Conrad, Xavier Estivill, Chris Tyler-Smith, Nigel P Carter, Hiroyuki Aburatani, Charles Lee, Keith W Jones, Stephen W Scherer, Matthew E Hurles
  • Deficiency in neuronal TGF-beta signaling promotes neurodegeneration and Alzheimer's pathology.
    J Clin Invest, Vol. 116, No. 11. (1 November 2006), pp. 3060-3069.
    by Ina Tesseur, Kun Zou, Luke Esposito, Frederique Bard, Elisabeth Berber, Judith Van V Can, Amy H H Lin, Leslie Crews, Patrick Tremblay, Paul Mathews, Lennart Mucke, Eliezer Masliah, Tony Wyss-Coray
    posted to alzheimer tgf by giovanni on 2006-11-22 17:59:11 as *** along with 1 group GeschwindLab
  • PGC-1alpha: a key regulator of energy metabolism.
    Adv Physiol Educ, Vol. 30, No. 4. (December 2006), pp. 145-151.
    by Huiyun Liang, Walter F F Ward
    posted to pgc1-alpha by giovanni on 2006-11-20 20:29:18 as *** along with 1 person and 1 group jyuh GeschwindLab
  • Utility of clinical criteria in differentiating frontotemporal lobar degeneration (FTLD) from AD.
    Neurology, Vol. 58, No. 11. (11 June 2002), pp. 1608-1615.
    by HJ Rosen, KM Hartikainen, W Jagust, JH Kramer, BR Reed, JL Cummings, K Boone, W Ellis, C Miller, BL Miller
    posted to diagnostic_criteria ftd by giovanni on 2006-11-06 16:58:51 as *** along with 1 group GeschwindLab
  • Identification of CSF biomarkers for frontotemporal dementia using SELDI-TOF.
    Exp Neurol, Vol. 196, No. 2. (December 2005), pp. 273-281.
    posted to biomarkers ftd by giovanni on 2006-11-06 16:55:17 as *** along with 1 group GeschwindLab
  • Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2.
    J Clin Invest, Vol. 116, No. 3. (March 2006), pp. 817-824.
    by DB Savage, CS Choi, VT Samuel, ZX Liu, D Zhang, A Wang, XM Zhang, GW Cline, XX Yu, JG Geisler, S Bhanot, BP Monia, GI Shulman
    posted to diabetes insulin_r by giovanni on 2006-11-05 16:08:50 as *** along with 1 group GeschwindLab
  • Design of Microarray Experiments for Genetical Genomics Studies
    Genetics, Vol. 174, No. 2. (1 October 2006), pp. 945-957.
    by Julio S Filho, Steven G Gilmour, Guilherme J Rosa
  • Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators.
    Cell, Vol. 127, No. 2. (20 October 2006), pp. 397-408.
    by J St-Pierre, S Drori, M Uldry, JM Silvaggi, J Rhee, S Jäger, C Handschin, K Zheng, J Lin, W Yang, DK Simon, R Bachoo, BM Spiegelman
    posted to neurodegeneration pgc1-alpha by giovanni on 2006-10-26 02:33:38 as *** along with 1 group GeschwindLab
  • Loss of apolipoprotein E receptor LR11 in Alzheimer disease.
    Arch Neurol, Vol. 61, No. 8. (August 2004), pp. 1200-1205.
    by CR Scherzer, K Offe, M Gearing, HD Rees, G Fang, CJ Heilman, C Schaller, H Bujo, AI Levey, JJ Lah
  • Genomics of Brain and Blood: Progress and Pitfalls
    Epilepsia, Vol. 47, No. 10. (October 2006), pp. 1603-1607.
  • Genomic profiles for human peripheral blood T cells, B cells, natural killer cells, monocytes, and polymorphonuclear cells: comparisons to ischemic stroke, migraine, and Tourette syndrome.
    Genomics, Vol. 87, No. 6. (June 2006), pp. 693-703.
    by X Du, Y Tang, H Xu, L Lit, W Walker, P Ashwood, JP Gregg, FR Sharp
  • Gene expression in blood changes rapidly in neutrophils and monocytes after ischemic stroke in humans: a microarray study.
    J Cereb Blood Flow Metab, Vol. 26, No. 8. (August 2006), pp. 1089-1102.
    by Y Tang, H Xu, X Du, L Lit, W Walker, A Lu, R Ran, JP Gregg, M Reilly, A Pancioli, JC Khoury, LR Sauerbeck, JA Carrozzella, J Spilker, J Clark, KR Wagner, EC Jauch, DJ Chang, P Verro, JP Broderick, FR Sharp
  • Cloning, genomic structure, and expression profiles of TULIP1 (GARNL1), a brain-expressed candidate gene for 14q13-linked neurological phenotypes, and its murine homologue.
    Genomics, Vol. 84, No. 3. (September 2004), pp. 577-586.
    posted to fahr by giovanni on 2006-10-25 23:04:43 as *** along with 1 group GeschwindLab
  • Identification of a locus on chromosome 14q for idiopathic basal ganglia calcification (Fahr disease).
    Am J Hum Genet, Vol. 65, No. 3. (September 1999), pp. 764-772.
    by DH Geschwind, M Loginov, JM Stern
    posted to fahr by giovanni on 2006-10-25 23:03:38 as *** along with 1 group GeschwindLab
  • What is and what is not 'Fahr's disease'.
    Parkinsonism Relat Disord, Vol. 11, No. 2. (March 2005), pp. 73-80.
    by BV Manyam
    posted to fahr by giovanni on 2006-10-25 22:58:34 as *** along with 1 group GeschwindLab
  • Genotyping pooled DNA using 100K SNP microarrays: a step towards genomewide association scans.
    Nucleic Acids Res, Vol. 34, No. 4. (2006)
    posted to affy snp_pool by giovanni on 2006-10-25 16:56:35 as *** along with 1 person and 1 group jyuh GeschwindLab
  • Locating mammalian transcription factor binding sites: A survey of computational and experimental techniques.
    Genome Res (19 October 2006)
    by Laura Elnitski, Victor X X Jin, Peggy J J Farnham, Steven J M J Jones
  • A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter.
    Science, Vol. 312, No. 5777. (26 May 2006), pp. 1215-1217.
    by M De Gobbi, V Viprakasit, JR Hughes, C Fisher, VJ Buckle, H Ayyub, RJ Gibbons, D Vernimmen, Y Yoshinaga, P de Jong, JF Cheng, EM Rubin, WG Wood, D Bowden, DR Higgs
  • Reelin, lipoprotein receptors and synaptic plasticity
    Nature Reviews Neuroscience, Vol. 7, No. 11., pp. 850-859.
    by Joachim Herz, Ying Chen
  • Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs
    Nat Med, Vol. 10, No. 10. (October 2004), pp. 1055-1063.
    by Mark S Forman, John Q Trojanowski, Virginia M Lee
    posted to neurodegeneration tau tau_review by giovanni on 2006-10-18 16:25:00 as *** along with 1 group GeschwindLab
  • GOLEM: an interactive graph-based gene-ontology navigation and analysis tool
    BMC Bioinformatics, Vol. 7 (10 October 2006), 443.
    by Rachel SG Sealfon, Matthew A Hibbs, Curtis Huttenhower, Chad L Myers, Olga G Troyanskaya
  • Glyoxalase 1 and glutathione reductase 1 regulate anxiety in mice
    Nature (23 October 2005)
    by Iiris Hovatta, Richard S Tennant, Robert Helton, Robert A Marr, Oded Singer, Jeffrey M Redwine, Julie A Ellison, Eric E Schadt, Inder M Verma, David J Lockhart, Carrolee Barlow
  • An integrative genomics approach to infer causal associations between gene expression and disease
    Nature Genetics, Vol. 37, No. 7. (19 June 2005), pp. 710-717.
    by Eric E Schadt, John Lamb, Xia Yang, Jun Zhu, Steve Edwards, Debraj Guhathakurta, Solveig K Sieberts, Stephanie Monks, Marc Reitman, Chunsheng Zhang, Pek Y Lum, Amy Leonardson, Rolf Thieringer, Joseph M Metzger, Liming Yang, John Castle, Haoyuan Zhu, Shera F Kash, Thomas A Drake, Alan Sachs, Aldons J Lusis
  • PGC-1 coactivators: inducible regulators of energy metabolism in health and disease.
    J Clin Invest, Vol. 116, No. 3. (March 2006), pp. 615-622.
    by BN Finck, DP Kelly
    posted to pgc1-alpha by giovanni on 2006-10-12 01:45:03 as *** along with 1 person and 1 group jyuh GeschwindLab
  • PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3.
    Nat Med, Vol. 10, No. 5. (May 2004), pp. 530-534.
    by SH Koo, H Satoh, S Herzig, CH Lee, S Hedrick, R Kulkarni, RM Evans, J Olefsky, M Montminy
    posted to diabetes ox_stress pgc1-alpha by giovanni on 2006-10-12 00:42:51 as *** along with 1 group GeschwindLab
  • The GAA triplet-repeat is unstable in the context of the human FXN locus and displays age-dependent expansions in cerebellum and DRG in a transgenic mouse model.
    Hum Genet (21 September 2006)
    by Rhonda M Clark, Irene De Biase, Anna P Malykhina, Sahar Al-Mahdawi, Mark Pook, Sanjay I Bidichandani
    posted to frda_model by giovanni on 2006-10-07 22:46:18 as *** along with 1 group GeschwindLab
  • A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration.
    Neuron, Vol. 51, No. 5. (7 September 2006), pp. 549-560.
    by SL Karsten, TK Sang, LT Gehman, S Chatterjee, J Liu, GM Lawless, S Sengupta, RW Berry, J Pomakian, HS Oh, C Schulz, KS Hui, M Wiedau-Pazos, HV Vinters, LI Binder, DH Geschwind, GR Jackson
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