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Forces of Interaction between DNA-Grafted Colloids: An Optical Tweezer Measurement

by: K Kegler, M Salomo, F Kremer
Physical Review Letters, Vol. 98, No. 5. (2007)


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Optical tweezers are employed to measure the forces of interaction between single DNA-grafted colloids. Parameters to be varied are the length of the DNA, the grafting density, and the ion concentration of the surrounding medium. From the measured force-separation dependence an interaction length at a given force is deduced. It shows in the mushroom regime a scaling with the grafting density which levels off for brushes. For the latter the transition from an osmotic to a salted brush can be traced in detail by varying the ion concentration in accordance with mean field theories.


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